Gastroprotective effect of the aqueous leaf extract of Guiera senegalensis in Albino rats

Objective:To evaluate the effect of aqueous leaf extract of Guiera senegalensis(G.senegalensis)on gastric mucosal damage using different ulcer models.Methods:Considering the above claims,the present study was undertaken to validate the gastroprotective potential of the aqueous leaf extract of this plant against ethanol,water immersion and Aspirin induced ulcer models.Results:The leaf extract(50,100 and 200 mg/kg,p.o.)significantly(P<0.05)decreased the ulcer index in all assays used.Conclusions:The results obtained,provide strong evidence of antiulcer activity of the leaf extract of G.senegalensis and support the traditional uses of the plant for the treatment of ulcer.