Monophosphoryl lipid A coating of hydroxyethyl starch nanocapsules drastically increases uptake and maturation by dendritic cells while minimizing the adjuvant dosage

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Veröffentlicht in:	Vaccine 2015-02, Vol.33 (7), p.838-846
Hauptverfasser:	Fichter, Michael, Dedters, Marvin, Pietrzak-Nguyen, Anette, Pretsch, Leah, Meyer, Claudius U, Strand, Susanne, Zepp, Fred, Baier, Grit, Landfester, Katharina, Gehring, Stephan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic Adsorption Allergy and Immunology Blood banks Cells, Cultured Cloning Cytokines Dendritic cell targeting Dendritic Cells - metabolism Drug delivery systems Humans Hydroxyethyl starch Hydroxyethyl Starch Derivatives - chemistry Immune system Interferon Interleukin-12 - metabolism Lipid A - analogs & derivatives Lipid A - chemistry Lipids Microscopy, Confocal Monophosphoryl lipid A Nanocapsules Nanocapsules - administration & dosage Nanocapsules - chemistry Nanomedicine - methods Studies Th1 Cells - metabolism TLR4 Toll-Like Receptor 4 - metabolism Vaccine Vaccines
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