Early-Onset Asthma Is Associated with a Specific Polymorphisms of TLR-4 (Asp299Gly) in Ukrainian Adults

Rationale Toll-like receptor 4 (TLR4) is the principal receptor for bacterial endotoxin and an important intracellular signal pathway of the innate immune response in asthma.

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Veröffentlicht in:Journal of allergy and clinical immunology 2015-02, Vol.135 (2), p.AB73-AB73
Hauptverfasser: Bisyuk, Yuri, Kurchenko, A.I, Beloglazov, V.a, Dubovyi, A.I, Znamenska, L.K, DuBuske, Lawrence M., MD, FAAAAI
Format: Artikel
Sprache:eng
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Zusammenfassung:Rationale Toll-like receptor 4 (TLR4) is the principal receptor for bacterial endotoxin and an important intracellular signal pathway of the innate immune response in asthma.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2014.12.1173