Assessment of pulmonary toxicity of MgO nanoparticles in rats

In this study, we have evaluated the pulmonary toxicity of MgO nanoparticles (MgO NPs) in rats following their exposure. NPs in phosphate buffered saline + 1% Tween 80 were exposed via intratracheal instillation at a doses of 1 mg/kg or 5 mg/kg into rat lungs and evaluated for various tissue damage...

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Veröffentlicht in:	Environmental toxicology 2015-03, Vol.30 (3), p.308-314
Hauptverfasser:	Gelli, Kiranmai, Porika, Mahendar, Anreddy, Rama Narsimha Reddy
Format:	Artikel
Sprache:	eng
Schlagworte:	alkaline phosphatase Alkaline Phosphatase - metabolism ALP Animals BAL fluid Bronchoalveolar Lavage Fluid - cytology dose response Dose-Response Relationship, Drug histology histopathology L-Lactate Dehydrogenase - metabolism lactate dehydrogenase LDH Lung - pathology Lung Diseases - chemically induced Lung Diseases - pathology lungs lymphocytes magnesium oxide Magnesium Oxide - toxicity Male MgO nanoparticles Nanoparticles - toxicity Neutrophil Infiltration - drug effects PBS polysorbates Quartz Quartz - toxicity Rats Rats, Wistar toxicity
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