Human Bronchial Epithelial Cell-Derived Factors from Severe Asthmatics Can Stimulate Local Eosinophilopoetic Responses

Rationale Bronchial epithelial cells activated by allergens, viruses or environmental pollutants produce cytokines including thymic stromal lymphopoietin (TSLP) and IL-33 that can initiate Th2 inflammatory processes.

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Veröffentlicht in:Journal of allergy and clinical immunology 2015-02, Vol.135 (2), p.AB148-AB148
Hauptverfasser: Smith, Steven G., PhD, Mukherjee, Manali, PhD, Irshad, Anam, Plante, Sophie, Gauvreau, Gail M., PhD, Nair, Parameswaran K., MD, PhD, FRCP, FRCPC, Chakir, Jamila, PhD, Sehmi, Roma, PhD, FAAAAI
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Sprache:eng
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Zusammenfassung:Rationale Bronchial epithelial cells activated by allergens, viruses or environmental pollutants produce cytokines including thymic stromal lymphopoietin (TSLP) and IL-33 that can initiate Th2 inflammatory processes.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2014.12.1420