Preliminary Study of Pancreatic Cancer Associated with Helicobacter pylori Infection

Little is known about the relationship about Helicobacter pylori ( H. pylori ) infection and pancreatic, and this study was set to investigate how H. pylori infection is correlated with pancreatic cancer and provide references for the clinical prevention and treatment of pancreatic cancer. 56 cases...

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Veröffentlicht in:Cell biochemistry and biophysics 2015-01, Vol.71 (1), p.397-400
Hauptverfasser: Ai, Fulu, Hua, Xiangdong, Liu, Yefu, Lin, Jie, Feng, Zhaoqiang
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Sprache:eng
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Zusammenfassung:Little is known about the relationship about Helicobacter pylori ( H. pylori ) infection and pancreatic, and this study was set to investigate how H. pylori infection is correlated with pancreatic cancer and provide references for the clinical prevention and treatment of pancreatic cancer. 56 cases of pancreatic cancer patients admitted to the hospital from August 2012 to August 2013 were collected as the observation group. The anti-Hp IgG ( H. pylori -specific antibodies), Hp IgM ( H. pylori antibodies), and CagA-Hp-IgG ( H. pylori serotoxin-associated protein a antibody) in the serum were measured and compared with the related indicators of control group (60 cases of healthy subjects). The H. pylori infection rate was 64.29 % in the observation group, and that in the control group was 46.67 %. Our results showed that the H. pylori infection rate in the observation group was significantly higher than that in the control group, which was statistically different ( P  
ISSN:1085-9195
1559-0283
DOI:10.1007/s12013-014-0211-2