Two new anti-fungal diterpenoids from the husks of Oryza sativa
•Two new (1 and 2) diterpenoids were isolated from husks of Oryza sativa.•Their structures were elucidated by spectroscopic means.•Compounds 1 and 2 showed anti-fungal activity against Magnaporthe grisea. A new pimarane diterpene 6β,19β-epoxy-3β-hydroxy-5α,9β-pimara-7,15-diene (1) and a new abietane...
Gespeichert in:
Veröffentlicht in: | Phytochemistry letters 2014-12, Vol.10, p.309-312 |
---|---|
Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | •Two new (1 and 2) diterpenoids were isolated from husks of Oryza sativa.•Their structures were elucidated by spectroscopic means.•Compounds 1 and 2 showed anti-fungal activity against Magnaporthe grisea.
A new pimarane diterpene 6β,19β-epoxy-3β-hydroxy-5α,9β-pimara-7,15-diene (1) and a new abietane diterpene 3β,20β-epoxy-3α-hydroxy-5α-abieta-8,11,13-trien-7-one (2) were isolated from the rice husks of Oryza sativa L. Their structures were elucidated on the basis of extensive spectroscopic analysis, including MS, 1D and 2D NMR techniques. Compounds 1 and 2 were found to show inhibitory activity against spore germination of Magnaporthe grisea with IC50 values 0.213 and 0.232mM, respectively. |
---|---|
ISSN: | 1874-3900 1876-7486 |
DOI: | 10.1016/j.phytol.2014.10.023 |