Effects of Dracaena arborea (Dracaenaceae) on sexual dysfunction in 4 weeks hyperglycemic male rats

To investigate the effects of Dracaena arborea (D. arborea) on the sexual behavior parameters in experienced type-1 diabetic rats. Aqueous and ethanol (100 and 500 mg/kg respectively) extracts of dried root barks of D. arborea, sildenafil citrate (1.44 mg/kg), trimethylamine-N-oxide (TMAO, 20 mg/kg)...

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Veröffentlicht in:Asian Pacific journal of tropical medicine 2014-08, Vol.7 (8), p.609-619
Hauptverfasser: Wankeu-Nya, M, Watcho, P, Nguelefack, T B, Carro-Juarez, M, Tapondjou, L, Kamanyi, A
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Sprache:eng
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Zusammenfassung:To investigate the effects of Dracaena arborea (D. arborea) on the sexual behavior parameters in experienced type-1 diabetic rats. Aqueous and ethanol (100 and 500 mg/kg respectively) extracts of dried root barks of D. arborea, sildenafil citrate (1.44 mg/kg), trimethylamine-N-oxide (TMAO, 20 mg/kg) and distilled water (10 mL/kg) were orally administered to 4 weeks streptozotocin-induced diabetic rats. Mount latency and frequency (ML, MF), intromission latency and frequency (IL, IF) and post-ejaculatory interval (PEI) were measured by ejaculatory series during 90 min once a week for 4 weeks. Glycemia was determined at the beginning and at the end of the treatment. D. arborea did not show any major antihyperglycemic effects. Compared to the control group, a significant (P
ISSN:1995-7645
2352-4146
DOI:10.1016/S1995-7645(14)60103-6