Imputation from 328 African Ancestry Genomes Reveals New Associations with Asthma in DPP10

Rationale The gene encoding dipeptidyl-peptidase 10 (DPP10) was originally identified as an asthma candidate gene through positional cloning and subsequently a genome-wide association study (GWAS) meta-analysis However, the precise DPP10 locus conferring risk to asthma is unclear.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of allergy and clinical immunology 2015-02, Vol.135 (2), p.AB162-AB162
Hauptverfasser:	Masuko, Hironori, MD, PhD, Rafaels, Nicholas M, Huang, Lili, MPH, Chavan, Sameer, MS, Wilson, James G., MD, Williams, L. Keoki, MD, MPH, FAAAAI, Ware, Lorraine B., MD, Ober, Carole, PhD, Meyers, Deborah A., PhD, FAAAAI, Hartert, Tina V., MD, MPH, Foreman, Marilyn, MD, MS, Ford, Jean G., MD, Burchard, Esteban Gonza, MD, MPH, Bleecker, Eugene R., MD, FAAAAI, Dunston, Georgia, Taub, Margaret, PhD, Beaty, Terri H., PhD, Ruczinski, Ingo, PhD, Mathias, Rasika A., ScD, Barnes, Kathleen C
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Genealogy Genes Genomes
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Rationale The gene encoding dipeptidyl-peptidase 10 (DPP10) was originally identified as an asthma candidate gene through positional cloning and subsequently a genome-wide association study (GWAS) meta-analysis However, the precise DPP10 locus conferring risk to asthma is unclear.
ISSN:	0091-6749 1097-6825
DOI:	10.1016/j.jaci.2014.12.1469