Experimental self-etching HEMA-free adhesive systems: cytotoxicity and degree of conversion

The aim of this study was to evaluate the effect of replacing 2-hydroxyethyl methacrylate (HEMA) by methacrylate surfactant monomers on the cytotoxicity and degree of conversion of two-step self-etching dentin adhesive systems. Five HEMA-free adhesive systems were tested: Bis-EMA 10, Bis-EMA 30, PEG...

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Veröffentlicht in:Journal of materials science. Materials in medicine 2015-01, Vol.26 (1), p.5370-8, Article 40
Hauptverfasser: Barbosa, Marília Oliveira, de Carvalho, Rodrigo Varella, Demarco, Flávio Fernando, Ogliari, Fabrício Aulo, Zanchi, Cesar Henrique, Piva, Evandro, da Silva, Adriana Fernandes
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Sprache:eng
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Zusammenfassung:The aim of this study was to evaluate the effect of replacing 2-hydroxyethyl methacrylate (HEMA) by methacrylate surfactant monomers on the cytotoxicity and degree of conversion of two-step self-etching dentin adhesive systems. Five HEMA-free adhesive systems were tested: Bis-EMA 10, Bis-EMA 30, PEG400, PEG400UDMA, PEG1000, and a HEMA group was used as positive control. The cytotoxicity of the experimental primers, with different monomer concentrations (2 or 20 wt%), and bond resins, containing 25 wt% surfactant, was assessed using murine fibroblast cell line 3T3 and the tetrazolium assay (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT)). The degree of conversion of the bond resins was analyzed using Fourier transform infrared spectroscopy. The data were submitted to statistical analysis using level of significance set at P  
ISSN:0957-4530
1573-4838
DOI:10.1007/s10856-014-5370-6