Oligopeptide-decorated liquid crystal droplets for detecting proteases

Oligopeptide-decorated liquid crystal droplets for detecting proteases

We prepared the bioactive liquid crystal (LC) droplets by decorating an oligopeptide at the LC/aqueous interface to stabilize the LC droplets. These LC droplets can be used to detect proteases through the specific cleavage of protease on an oligopeptide leading to a bipolar-to-radial transition of L...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chemical communications (Cambridge, England) England), 2014-10, Vol.50 (81), p.12162-12165
Hauptverfasser: Chang, Chung-Yun, Chen, Chih-Hsin
Format: Artikel
Sprache:eng
Schlagworte:
Amino Acid Sequence
Biocompatibility
Carbocyanines - chemistry
Chymotrypsin - analysis
Chymotrypsin - metabolism
Cleavage
Decoration
Droplets
Ductile brittle transition
Fluorescent Dyes - chemistry
Fracture mechanics
Liquid crystals
Liquid Crystals - chemistry
Molecular Sequence Data
Oligopeptides - chemistry
Oligopeptides - metabolism
Peptide Hydrolases - analysis
Peptide Hydrolases - metabolism
Protease
Spectrometry, Fluorescence
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:We prepared the bioactive liquid crystal (LC) droplets by decorating an oligopeptide at the LC/aqueous interface to stabilize the LC droplets. These LC droplets can be used to detect proteases through the specific cleavage of protease on an oligopeptide leading to a bipolar-to-radial transition of LC configuration inside the droplets.
ISSN:1359-7345
1364-548X
DOI:10.1039/c4cc04651j