No Relationship of Lipid-Lowering Agents to Hematoma Growth: Pooled Analysis of the Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trials Studies

BACKGROUND AND PURPOSE—Controversy persists over statins and risk of intracerebral hemorrhage. We determined associations of premorbid lipid-lowering therapy and outcomes among participants of the Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trials (INTERACT). METHODS—The pooled d...

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Veröffentlicht in:	Stroke (1970) 2015-03, Vol.46 (3), p.857-859
Hauptverfasser:	Priglinger, Miriam, Arima, Hisatomi, Anderson, Craig, Krause, Martin
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Adult Aged Antihypertensive Agents - therapeutic use Blood Pressure Brain - physiopathology Cerebral Hemorrhage - blood Cerebral Hemorrhage - complications Cerebral Hemorrhage - diagnosis Data Interpretation, Statistical Female Hematoma - diagnostic imaging Hematoma - drug therapy Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Hypertension - complications International Cooperation Lipids - blood Male Middle Aged Multivariate Analysis Prospective Studies Systole Tomography, X-Ray Computed Treatment Outcome
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Zusammenfassung:	BACKGROUND AND PURPOSE—Controversy persists over statins and risk of intracerebral hemorrhage. We determined associations of premorbid lipid-lowering therapy and outcomes among participants of the Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trials (INTERACT). METHODS—The pooled data of INTERACT 1 and 2 (international, multicenter, prospective, open, blinded end point, randomized controlled trials of patients with intracerebral hemorrhage [
ISSN:	0039-2499 1524-4628
DOI:	10.1161/STROKEAHA.114.007664