Single injection of the β2 -adrenergic receptor agonist, clenbuterol, into newly hatched chicks alters abdominal fat pad mass in growing birds

Highlights • Clenbuterol injection into 1-day-old chicks decreased the abdominal fat during growth. • Small adipocyte-like cells were observed in the clenbuterol-injected chicks. • Clenbuterol injection decreased genes required for adipogenesis in the abdominal fat. • Clenbuterol injection decreased...

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Veröffentlicht in:	General and comparative endocrinology 2015-01, Vol.211, p.9-13
Hauptverfasser:	Ishimaru, Yoshitaka, Ijiri, Daichi, Shimamoto, Saki, Ishitani, Kanae, Nojima, Tsutomu, Ohtsuka, Akira
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdominal Fat - drug effects Abdominal Fat - growth & development Adipocytes Adipose tissue Adipose Tissue - drug effects Adipose Tissue - growth & development Adrenergic beta-Agonists - administration & dosage Adrenergic beta-Agonists - pharmacology Animals Body Weight - drug effects Chicken Chickens - blood Chickens - genetics Chickens - growth & development Clenbuterol - administration & dosage Clenbuterol - pharmacology Endocrinology & Metabolism Fatty Acid Synthases - metabolism Gene Expression Regulation, Developmental - drug effects Lipid metabolism Liver - drug effects Liver - metabolism Male Organ Size - drug effects Receptors adrenergic beta-2 RNA, Messenger - metabolism
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Zusammenfassung:	Highlights • Clenbuterol injection into 1-day-old chicks decreased the abdominal fat during growth. • Small adipocyte-like cells were observed in the clenbuterol-injected chicks. • Clenbuterol injection decreased genes required for adipogenesis in the abdominal fat. • Clenbuterol injection decreased fatty acid synthase in the abdominal fat.
ISSN:	0016-6480 1095-6840
DOI:	10.1016/j.ygcen.2014.12.002