The usefulness of a disease severity staging classification system for IPF in Japan: 20 years of experience from empirical evidence to randomized control trial enrollment

The usefulness of a disease severity staging classification system for IPF in Japan: 20 years of experience from empirical evidence to randomized control trial enrollment

Abstract Since 1991, the severity of idiopathic pulmonary fibrosis (IPF) has been classified into 4 stages—stage I (characterized by a resting PaO2 ≥80 Torr), stage II (70–79 Torr), stage III (60–69 Torr), or stage IV (

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Veröffentlicht in:Respiratory investigation 2015-01, Vol.53 (1), p.7-12
Hauptverfasser: Homma, Sakae, Sugino, Keishi, Sakamoto, Susumu
Format: Artikel
Sprache:eng
Schlagworte:
Acetylcysteine - therapeutic use
Acute exacerbation
Disease severity stage
Empirical Research
Evidence-Based Medicine
Humans
Idiopathic pulmonary fibrosis
Idiopathic Pulmonary Fibrosis - classification
Idiopathic Pulmonary Fibrosis - diagnosis
Idiopathic Pulmonary Fibrosis - drug therapy
Internal Medicine
Japan
Oximetry
Patient Selection
Pulmonary/Respiratory
Pyridones - therapeutic use
Randomized controlled trial practice
Randomized Controlled Trials as Topic
Severity of Illness Index
Survival
Time Factors
Vital Capacity
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Zusammenfassung:Abstract Since 1991, the severity of idiopathic pulmonary fibrosis (IPF) has been classified into 4 stages—stage I (characterized by a resting PaO2 ≥80 Torr), stage II (70–79 Torr), stage III (60–69 Torr), or stage IV (
ISSN:2212-5345
2212-5353
DOI:10.1016/j.resinv.2014.08.003