The Association between Aortic Distensibility and Coronary Flow Reserve in Newly Diagnosed Diabetic Patients

Introduction Aortic distensibility (AD) is an important parameter affecting coronary hemodynamics. Coronary flow velocity reserve (CFVR) is a reliable marker of coronary endothelial function in diabetic patients. The aim of this study was to investigate the association between AD and CFVR in newly diagnosed diabetic patients. Method We studied 77 patients with newly diagnosed diabetes mellitus (DM) and 30 age‐ and sex‐matched healthy control subjects. CFVR was calculated as the hyperemic to resting coronary diastolic velocities ratio by using transthoracic echocardiography. Pulse pressure (PP) and AD were calculated. Results Fasting blood glucose, HbA1c and PP were significantly higher in patients with diabetes (P