Cholesterol Crystals Associate With Coronary Plaque Vulnerability In Vivo

Cholesterol crystals on FD-OCT are not histopathologically validated. Because of the relatively small study population, a larger study is required to elucidate the effect of cholesterol crystals on clinical outcome. In summary, cholesterol crystals within target vessels requiring percutaneous corona...

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Veröffentlicht in:	Journal of the American College of Cardiology 2015-02, Vol.65 (6), p.630-632
Hauptverfasser:	Kataoka, Yu, MD, Puri, Rishi, MBBS, PhD, Hammadah, Muhammad, MD, Duggal, Bhanu, MD, Uno, Kiyoko, MD, PhD, Kapadia, Samir R., MD, Tuzcu, E. Murat, MD, Nissen, Steven E., MD, Nicholls, Stephen J., MBBS, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Cardiology Cardiovascular Cardiovascular disease Cholesterol Cholesterol - metabolism Coronary Artery Disease - diagnosis Coronary Artery Disease - metabolism Coronary vessels Coronary Vessels - metabolism Diagnostic Imaging - methods Humans Internal Medicine Lipids Plaque, Atherosclerotic - diagnosis Plaque, Atherosclerotic - metabolism
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Zusammenfassung:	Cholesterol crystals on FD-OCT are not histopathologically validated. Because of the relatively small study population, a larger study is required to elucidate the effect of cholesterol crystals on clinical outcome. In summary, cholesterol crystals within target vessels requiring percutaneous coronary intervention were observed in 39.6% of patients with stable coronary artery disease.
ISSN:	0735-1097 1558-3597
DOI:	10.1016/j.jacc.2014.11.039