Detection of a cell-cycle inhibitor of Petunia hybrida protoplasts in an Arthrospira platensis extract

A chloroform crude extract of whole Arthrospira platensis cells, provisionally named A. platensis auto-inhibitor (APAI), was inhibitory to growth of human prostatic cells and was toxic to them at less than 25 μg/ml. With cultured protoplasts of Petunia hybrida, APAI was growth inhibitory, without cy...

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Veröffentlicht in:Biotechnology letters 1998-06, Vol.20 (6), p.557-560
Hauptverfasser: HOURS, M. C, LINARES, P. N, THI HAI PHAN, FILALI-MOUHIM, R
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container_title Biotechnology letters
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creator HOURS, M. C
LINARES, P. N
THI HAI PHAN
FILALI-MOUHIM, R
description A chloroform crude extract of whole Arthrospira platensis cells, provisionally named A. platensis auto-inhibitor (APAI), was inhibitory to growth of human prostatic cells and was toxic to them at less than 25 μg/ml. With cultured protoplasts of Petunia hybrida, APAI was growth inhibitory, without cytotoxicity, at 500 μg/ml. Using flow cytometry, it was seen that APAI induced arrest of the plant cell division cycle at the G1 phase. © Rapid Science Ltd. 1998[PUBLICATION ABSTRACT]
doi_str_mv 10.1023/A:1005345627274
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subjects Arthrospira platensis
Biological and medical sciences
Biology of microorganisms of confirmed or potential industrial interest
Biotechnology
Cell division
Chloroform
Cytotoxicity
Fundamental and applied biological sciences. Psychology
Miscellaneous
Mission oriented research
Petunia hybrida
title Detection of a cell-cycle inhibitor of Petunia hybrida protoplasts in an Arthrospira platensis extract
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