mimicMe: a web server for prediction and analysis of host-like proteins in microbial pathogens

mimicMe is a web server for prediction and analysis of host-like proteins (mimics) encoded by microbial pathogens. Users select a host species and any set of pathogen and control proteomes (bacterial, fungal, protozoan or viral) and mimicMe reports host-like proteins that are unique to or enriched a...

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Veröffentlicht in:	Bioinformatics (Oxford, England) England), 2015-02, Vol.31 (4), p.590-592
Hauptverfasser:	Petrenko, Pavel, Doxey, Andrew C
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Bacteria - genetics Bacteria - metabolism Bacteria - pathogenicity Bacterial Infections - genetics Bacterial Infections - metabolism Bacterial Infections - microbiology Bacterial Proteins - genetics Bacterial Proteins - metabolism Host-Pathogen Interactions Humans Molecular Mimicry - genetics Molecular Sequence Data Proteome - analysis Sequence Homology, Amino Acid Software Virulence Factors - genetics Virulence Factors - metabolism
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Beschreibung
Zusammenfassung:	mimicMe is a web server for prediction and analysis of host-like proteins (mimics) encoded by microbial pathogens. Users select a host species and any set of pathogen and control proteomes (bacterial, fungal, protozoan or viral) and mimicMe reports host-like proteins that are unique to or enriched among pathogens. Additional server features include visualization of structural similarities between pathogen and host proteins as well as function-enrichment analysis. mimicMe is available at http://mimicme.uwaterloo.ca acdoxey@uwaterloo.ca.
ISSN:	1367-4803 1367-4811
DOI:	10.1093/bioinformatics/btu681