Paper – a potential platform in pharmaceutical development

Highlights • We revisit the process of drug discovery and the obstacles to success. • We summarize the applications of paper-based bioassays. • We examine the impact of paper-based platforms on in vitro pre-compound screening.

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Bibliographische Detailangaben
Veröffentlicht in:	Trends in biotechnology (Regular ed.) 2015-01, Vol.33 (1), p.4-9
Hauptverfasser:	Chen, Yi-Hsun, Kuo, Zong-Keng, Cheng, Chao-Min
Format:	Artikel
Sprache:	eng
Schlagworte:	Assaying bioassay Bioassays Capillarity Cell Culture Techniques Cellulose Cellulose fibers clinically based diagnostics in hospital Diagnostic software diagnostics Drug Discovery Drug Evaluation, Preclinical - methods Economics Internal Medicine Metabolic disorders Microfluidic Analytical Techniques Nucleic acids Obstacles paper-based microfluidic device Pharmaceutical industry Pharmaceuticals Platforms point-of-care diagnostics translational medicine Vascular endothelial growth factor
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Beschreibung
Zusammenfassung:	Highlights • We revisit the process of drug discovery and the obstacles to success. • We summarize the applications of paper-based bioassays. • We examine the impact of paper-based platforms on in vitro pre-compound screening.
ISSN:	0167-7799 1879-3096
DOI:	10.1016/j.tibtech.2014.11.004