The preoperative lymphocyte to monocyte ratio predicts clinical outcomes in patients with stage II/III gastric cancer

The preoperative lymphocyte to monocyte ratio predicts clinical outcomes in patients with stage II/III gastric cancer

Recently, lymphocyte to monocyte ratio (LMR) has been reported to be associated with clinical outcomes in some types of cancer but has not been explored in gastric cancer. In this study, we analyzed the association between LMR and clinical outcomes in stage II/III gastric cancer patients. Preoperati...

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Veröffentlicht in:Tumor biology 2014-11, Vol.35 (11), p.11659-11666
Hauptverfasser: Zhou, Xin, Du, Yiping, Xu, Jun, Huang, Zebo, Qiu, Tianzhu, Wang, Xiaping, Qian, Jiaqi, Zhu, Wei, Liu, Ping
Format: Artikel
Sprache:eng
Schlagworte:
Biomedical and Life Sciences
Biomedicine
Cancer Research
Cancer surgery
Clinical outcomes
Combined Modality Therapy
Female
Follow-Up Studies
Gastric cancer
Humans
Leukocytes
Lymphocytes
Lymphocytes - pathology
Male
Medical prognosis
Middle Aged
Monocytes - pathology
Neoplasm Recurrence, Local - mortality
Neoplasm Recurrence, Local - pathology
Neoplasm Recurrence, Local - therapy
Neoplasm Staging
Preoperative Care
Prognosis
Research Article
Retrospective Studies
ROC Curve
Stomach Neoplasms - mortality
Stomach Neoplasms - pathology
Stomach Neoplasms - therapy
Surgical outcomes
Survival Rate
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Zusammenfassung:Recently, lymphocyte to monocyte ratio (LMR) has been reported to be associated with clinical outcomes in some types of cancer but has not been explored in gastric cancer. In this study, we analyzed the association between LMR and clinical outcomes in stage II/III gastric cancer patients. Preoperative LMR calculated from peripheral lymphocyte and monocyte with corresponding clinical features from 426 stage II/III gastric cancer patients was noted. Kaplan–Meier method and Cox regression model were applied for overall survival (OS) and recurrence-free survival (RFS). Related with smaller tumor size ( p  
ISSN:1010-4283
1423-0380
DOI:10.1007/s13277-014-2504-x