Generalized Bullous Eruption after Routine Vaccination in a Child with Diffuse Cutaneous Mastocytosis
At 5 months of age, the patient received his scheduled 4-month vaccinations, including Haemophilus influenzae; protein-conjugated pneumococcal vaccine; poliomyelitis vaccine; diphtheria, pertussis, and tetanus toxoid; and rotavirus vaccine. Mast stell stabilizers such as cromolyn improve disease con...
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Veröffentlicht in: | The journal of allergy and clinical immunology in practice (Cambridge, MA) MA), 2013-01, Vol.1 (1), p.94-96 |
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creator | Bankova, Lora G., MD Walter, Jolan E., MD, PhD Iyengar, Shuba R., MD Lorenzo, Mayra E., MD, PhD Hornick, Jason L., MD, PhD Castells, Mariana C., MD, PhD |
description | At 5 months of age, the patient received his scheduled 4-month vaccinations, including Haemophilus influenzae; protein-conjugated pneumococcal vaccine; poliomyelitis vaccine; diphtheria, pertussis, and tetanus toxoid; and rotavirus vaccine. Mast stell stabilizers such as cromolyn improve disease control.9 In our experience, steroids are the preferred therapy for cases with blister formation, as has been previously reported in the literature.5 Our report shows the importance of considering all triggers for activation and degranulation in children with DCM. Besides anaphylaxis, severe generalized blister formation is also considered a life-threatening event, especially if evolving into the hemorrhagic form. |
doi_str_mv | 10.1016/j.jaip.2012.08.008 |
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Mast stell stabilizers such as cromolyn improve disease control.9 In our experience, steroids are the preferred therapy for cases with blister formation, as has been previously reported in the literature.5 Our report shows the importance of considering all triggers for activation and degranulation in children with DCM. Besides anaphylaxis, severe generalized blister formation is also considered a life-threatening event, especially if evolving into the hemorrhagic form.</description><identifier>ISSN: 2213-2198</identifier><identifier>EISSN: 2213-2201</identifier><identifier>DOI: 10.1016/j.jaip.2012.08.008</identifier><identifier>PMID: 24229828</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Abdomen ; Adrenal Cortex Hormones - therapeutic use ; Allergy and Immunology ; Anti-Asthmatic Agents - therapeutic use ; Biopsy ; Blister - drug therapy ; Blister - etiology ; Blood ; Cromolyn Sodium - therapeutic use ; Exanthema - drug therapy ; Exanthema - etiology ; Humans ; Immunization ; Infant ; Internal Medicine ; Laboratories ; Male ; Mastocytosis, Cutaneous - complications ; Mastocytosis, Cutaneous - diagnosis ; Mastocytosis, Cutaneous - pathology ; Mortality ; Pediatrics ; Vaccination - adverse effects ; Vaccines</subject><ispartof>The journal of allergy and clinical immunology in practice (Cambridge, MA), 2013-01, Vol.1 (1), p.94-96</ispartof><rights>American Academy of Allergy, Asthma & Immunology</rights><rights>2012 American Academy of Allergy, Asthma & Immunology</rights><rights>Copyright Elsevier Limited Jan 2013</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c516t-23848937beec9db9b2450ded1e871cae7d670643635ed8fae102869907359cef3</citedby><cites>FETCH-LOGICAL-c516t-23848937beec9db9b2450ded1e871cae7d670643635ed8fae102869907359cef3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,782,786,27933,27934</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24229828$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bankova, Lora G., MD</creatorcontrib><creatorcontrib>Walter, Jolan E., MD, PhD</creatorcontrib><creatorcontrib>Iyengar, Shuba R., MD</creatorcontrib><creatorcontrib>Lorenzo, Mayra E., MD, PhD</creatorcontrib><creatorcontrib>Hornick, Jason L., MD, PhD</creatorcontrib><creatorcontrib>Castells, Mariana C., MD, PhD</creatorcontrib><title>Generalized Bullous Eruption after Routine Vaccination in a Child with Diffuse Cutaneous Mastocytosis</title><title>The journal of allergy and clinical immunology in practice (Cambridge, MA)</title><addtitle>J Allergy Clin Immunol Pract</addtitle><description>At 5 months of age, the patient received his scheduled 4-month vaccinations, including Haemophilus influenzae; protein-conjugated pneumococcal vaccine; poliomyelitis vaccine; diphtheria, pertussis, and tetanus toxoid; and rotavirus vaccine. Mast stell stabilizers such as cromolyn improve disease control.9 In our experience, steroids are the preferred therapy for cases with blister formation, as has been previously reported in the literature.5 Our report shows the importance of considering all triggers for activation and degranulation in children with DCM. Besides anaphylaxis, severe generalized blister formation is also considered a life-threatening event, especially if evolving into the hemorrhagic form.</description><subject>Abdomen</subject><subject>Adrenal Cortex Hormones - therapeutic use</subject><subject>Allergy and Immunology</subject><subject>Anti-Asthmatic Agents - therapeutic use</subject><subject>Biopsy</subject><subject>Blister - drug therapy</subject><subject>Blister - etiology</subject><subject>Blood</subject><subject>Cromolyn Sodium - therapeutic use</subject><subject>Exanthema - drug therapy</subject><subject>Exanthema - etiology</subject><subject>Humans</subject><subject>Immunization</subject><subject>Infant</subject><subject>Internal Medicine</subject><subject>Laboratories</subject><subject>Male</subject><subject>Mastocytosis, Cutaneous - complications</subject><subject>Mastocytosis, Cutaneous - diagnosis</subject><subject>Mastocytosis, Cutaneous - pathology</subject><subject>Mortality</subject><subject>Pediatrics</subject><subject>Vaccination - adverse effects</subject><subject>Vaccines</subject><issn>2213-2198</issn><issn>2213-2201</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkl1rFDEUhgdRbKn9A15IwBtvdkwyyUwCIujaVqEi-HUbsskZmjE7WfNhWX-9GbdV6IXmJiHned98vKdpHhPcEkz651M7abdrKSa0xaLFWNxrjikl3YrWvfu3ayLFUXOa0oTrEGTADD9sjiijVAoqjhu4gBmi9u4nWPS6eB9KQmex7LILM9Jjhog-hpLdDOirNsbN-nfF1SJaXzlv0bXLV-iNG8eSAK1L1jMsJu91ysHsc0guPWoejNonOL2ZT5ov52ef129Xlx8u3q1fXa4MJ31e0U4wIbthA2Ck3cgNZRxbsATEQIyGwfYD7lnXdxysGDUQTEUvJR46Lg2M3Unz7OC7i-F7gZTV1iUD3h_upEjPWS8p6-n_UcYl4YKIoaJP76BTKHGuD6mGjA-UM8YqRQ-UiSGlCKPaRbfVca8IVktkalJLZGqJTGGhah5V9OTGumy2YP9IbgOqwIsDAPXbfjiIKhkHswHrIpisbHD_9n95R268m53R_hvsIf19h0pVoz4tTbP0DKG1XUg9_xfGvbs4</recordid><startdate>20130101</startdate><enddate>20130101</enddate><creator>Bankova, Lora G., MD</creator><creator>Walter, Jolan E., MD, PhD</creator><creator>Iyengar, Shuba R., MD</creator><creator>Lorenzo, Mayra E., MD, PhD</creator><creator>Hornick, Jason L., MD, PhD</creator><creator>Castells, Mariana C., MD, PhD</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><scope>7T5</scope><scope>H94</scope></search><sort><creationdate>20130101</creationdate><title>Generalized Bullous Eruption after Routine Vaccination in a Child with Diffuse Cutaneous Mastocytosis</title><author>Bankova, Lora G., MD ; Walter, Jolan E., MD, PhD ; Iyengar, Shuba R., MD ; Lorenzo, Mayra E., MD, PhD ; Hornick, Jason L., MD, PhD ; Castells, Mariana C., MD, PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c516t-23848937beec9db9b2450ded1e871cae7d670643635ed8fae102869907359cef3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2013</creationdate><topic>Abdomen</topic><topic>Adrenal Cortex Hormones - therapeutic use</topic><topic>Allergy and Immunology</topic><topic>Anti-Asthmatic Agents - therapeutic use</topic><topic>Biopsy</topic><topic>Blister - drug therapy</topic><topic>Blister - etiology</topic><topic>Blood</topic><topic>Cromolyn Sodium - therapeutic use</topic><topic>Exanthema - drug therapy</topic><topic>Exanthema - etiology</topic><topic>Humans</topic><topic>Immunization</topic><topic>Infant</topic><topic>Internal Medicine</topic><topic>Laboratories</topic><topic>Male</topic><topic>Mastocytosis, Cutaneous - complications</topic><topic>Mastocytosis, Cutaneous - diagnosis</topic><topic>Mastocytosis, Cutaneous - pathology</topic><topic>Mortality</topic><topic>Pediatrics</topic><topic>Vaccination - adverse effects</topic><topic>Vaccines</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bankova, Lora G., MD</creatorcontrib><creatorcontrib>Walter, Jolan E., MD, PhD</creatorcontrib><creatorcontrib>Iyengar, Shuba R., MD</creatorcontrib><creatorcontrib>Lorenzo, Mayra E., MD, PhD</creatorcontrib><creatorcontrib>Hornick, Jason L., MD, PhD</creatorcontrib><creatorcontrib>Castells, Mariana C., MD, PhD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><jtitle>The journal of allergy and clinical immunology in practice (Cambridge, MA)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bankova, Lora G., MD</au><au>Walter, Jolan E., MD, PhD</au><au>Iyengar, Shuba R., MD</au><au>Lorenzo, Mayra E., MD, PhD</au><au>Hornick, Jason L., MD, PhD</au><au>Castells, Mariana C., MD, PhD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Generalized Bullous Eruption after Routine Vaccination in a Child with Diffuse Cutaneous Mastocytosis</atitle><jtitle>The journal of allergy and clinical immunology in practice (Cambridge, MA)</jtitle><addtitle>J Allergy Clin Immunol Pract</addtitle><date>2013-01-01</date><risdate>2013</risdate><volume>1</volume><issue>1</issue><spage>94</spage><epage>96</epage><pages>94-96</pages><issn>2213-2198</issn><eissn>2213-2201</eissn><abstract>At 5 months of age, the patient received his scheduled 4-month vaccinations, including Haemophilus influenzae; 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subjects | Abdomen Adrenal Cortex Hormones - therapeutic use Allergy and Immunology Anti-Asthmatic Agents - therapeutic use Biopsy Blister - drug therapy Blister - etiology Blood Cromolyn Sodium - therapeutic use Exanthema - drug therapy Exanthema - etiology Humans Immunization Infant Internal Medicine Laboratories Male Mastocytosis, Cutaneous - complications Mastocytosis, Cutaneous - diagnosis Mastocytosis, Cutaneous - pathology Mortality Pediatrics Vaccination - adverse effects Vaccines |
title | Generalized Bullous Eruption after Routine Vaccination in a Child with Diffuse Cutaneous Mastocytosis |
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