Negative affectivity predicts decreased pain tolerance during low-grade inflammation in healthy women
Highlights • Stress sensitivity and immune activation interacted to increase sensitivity to pain. • Trait negative affect predicted lower pain tolerance under induced mild inflammation. • This interaction suggests a mechanism that may underlie functional pain symptoms.
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Veröffentlicht in: | Brain, behavior, and immunity behavior, and immunity, 2015-02, Vol.44, p.32-36 |
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container_title | Brain, behavior, and immunity |
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creator | Lacourt, T.E Houtveen, J.H Veldhuijzen van Zanten, J.J.C.S Bosch, J.A Drayson, M.T Van Doornen, L.J.P |
description | Highlights • Stress sensitivity and immune activation interacted to increase sensitivity to pain. • Trait negative affect predicted lower pain tolerance under induced mild inflammation. • This interaction suggests a mechanism that may underlie functional pain symptoms. |
doi_str_mv | 10.1016/j.bbi.2014.10.003 |
format | Article |
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subjects | Adolescent Adult Affect Algometry Allergy and Immunology Cross-Over Studies Cytokines Experimental pain Female Human Humans Inflammation Inflammation - psychology Inflammatory response Interleukin-6 Life events Negative affect Negative affectivity Pain sensitivity Pain threshold Pain Threshold - psychology Pain tolerance Placebo Pressure pain Psychiatry Randomized control Salmonella typhi Stress Stress, Psychological Vaccination Vaccine Young Adult |
title | Negative affectivity predicts decreased pain tolerance during low-grade inflammation in healthy women |
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