Hepatitis B immunity in teenagers vaccinated as infants: an Italian 17-year follow-up study

Hepatitis B immunity in teenagers vaccinated as infants: an Italian 17-year follow-up study

We assessed the persistence of hepatitis B surface antigen antibody (anti-HBs) and immune memory in a cohort of 571 teenagers vaccinated against hepatitis B as infants, 17 years earlier. Vaccinees were followed-up in 2003 and in 2010 (i.e. 10 years and 17 years after primary vaccination, respectivel...

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Veröffentlicht in:Clinical microbiology and infection 2014-10, Vol.20 (10), p.O680-O686
Hauptverfasser: Spada, E., Romanò, L., Tosti, M.E., Zuccaro, O., Paladini, S., Chironna, M., Coppola, R.C., Cuccia, M., Mangione, R., Marrone, F., Negrone, F.S., Parlato, A., Zamparo, E., Zotti, C.M., Mele, A., Zanetti, A.R.
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Booster
Female
Follow-Up Studies
Hepatitis
hepatitis B
Hepatitis B - immunology
Hepatitis B - prevention & control
Hepatitis B Antibodies - immunology
Hepatitis B Surface Antigens - immunology
Hepatitis B Vaccines - administration & dosage
Hepatitis B Vaccines - immunology
Hepatitis B virus
Humans
immune memory
Immunization, Secondary
Immunologic Memory
Infant
Italy
long-term protection
Male
Medical research
vaccination
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Zusammenfassung:We assessed the persistence of hepatitis B surface antigen antibody (anti-HBs) and immune memory in a cohort of 571 teenagers vaccinated against hepatitis B as infants, 17 years earlier. Vaccinees were followed-up in 2003 and in 2010 (i.e. 10 years and 17 years after primary vaccination, respectively). When tested in 2003, 199 vaccinees (group A) had anti-HBs
ISSN:1198-743X
1469-0691
DOI:10.1111/1469-0691.12591