Rubella and pregnancy: diagnosis, management and outcomes

What's already known about this topic?Congenital rubella is rare in developed countries, but potentially devastating fetal complications can occur. What does this study add?Once rubella is suspected in a pregnant woman, management is based on biological diagnosis, which should be performed in s...

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Veröffentlicht in:Prenatal diagnosis 2014-12, Vol.34 (13), p.1246-1253
Hauptverfasser: Bouthry, Elise, Picone, Olivier, Hamdi, Ghada, Grangeot-Keros, Liliane, Ayoubi, Jean-Marc, Vauloup-Fellous, Christelle
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Sprache:eng
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Zusammenfassung:What's already known about this topic?Congenital rubella is rare in developed countries, but potentially devastating fetal complications can occur. What does this study add?Once rubella is suspected in a pregnant woman, management is based on biological diagnosis, which should be performed in specialized laboratories.There is a lack of data concerning the ultrasound semiology of congenital rubella.Vaccination against rubella must be improved, especially in developing countries. ABSTRACT Rubella is a mild viral disease that typically occurs in childhood. Rubella infection during pregnancy causes congenital rubella syndrome, including the classic triad of cataracts, cardiac abnormalities and sensorineural deafness. Highly effective vaccines have been developed since 1969, and vaccination campaigns have been established in many countries. Although there has been progress, the prevention and diagnosis of rubella remain problematic. This article reviews the implications and management of rubella during pregnancy. © 2014 John Wiley & Sons, Ltd.
ISSN:0197-3851
1097-0223
DOI:10.1002/pd.4467