The Effects of Vitamin D Insufficiency and Seasonal Decrease on Cognition

Vitamin D3 (cholecalciferol) deficiency has been associated with dementia and cognitive decline. Which cognitive domains are most associated with D3 levels and how seasonal fluctuations in levels relate to cognition is unclear. We addressed these questions using a prospective observational study exa...

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Veröffentlicht in:	Canadian journal of neurological sciences 2014-07, Vol.41 (4), p.459-465
Hauptverfasser:	Pettersen, Jacqueline A., Fontes, Sara, Duke, Carlie L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Cholecalciferol - blood Cognition Disorders - blood Cognition Disorders - epidemiology Cognition Disorders - psychology Cross-Sectional Studies Female Humans Longitudinal Studies Male Middle Aged Original Article Prospective Studies Seasons Vitamin D Deficiency - blood Vitamin D Deficiency - epidemiology Vitamin D Deficiency - psychology Young Adult
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Zusammenfassung:	Vitamin D3 (cholecalciferol) deficiency has been associated with dementia and cognitive decline. Which cognitive domains are most associated with D3 levels and how seasonal fluctuations in levels relate to cognition is unclear. We addressed these questions using a prospective observational study examining associations between D3 levels and cognition among individuals living in northern latitudes (54°N) in summer and winter. Healthy adult participants underwent testing in summer and winter of D3 levels and cognition, using the Symbol digit Modalities test, phonemic fluency, digit Span and CANTAB battery. Of 32 participants tested in the summer, 46% were D3 insufficient (
ISSN:	0317-1671 2057-0155
DOI:	10.1017/S0317167100018497