Antiviral activity in vitro of Cupressus sempervirens on two human retroviruses HIV and HTLV

A proanthocyanidin polymer fraction (MW 1500–2000 daltons) from Cupressus sempervirens L. (Cupressaceae) exhibited true antiviral activity in vitro against two retroviruses, HIV and HTLV III B. In comparison with AZT no toxicity was observed with PPC at concentrations of 50 μg/mL which exceeded the...

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Veröffentlicht in:	Phytotherapy research 1998-08, Vol.12 (5), p.367-368
Hauptverfasser:	Amouroux, Pierre, Jean, Daniel, Lamaison, Jean-Louis
Format:	Artikel
Sprache:	eng
Schlagworte:	anti-HIV activity anti-HTLV activity Biological and medical sciences Cupressus sempervirens General pharmacology Medical sciences Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments procyanidin polymers
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Zusammenfassung:	A proanthocyanidin polymer fraction (MW 1500–2000 daltons) from Cupressus sempervirens L. (Cupressaceae) exhibited true antiviral activity in vitro against two retroviruses, HIV and HTLV III B. In comparison with AZT no toxicity was observed with PPC at concentrations of 50 μg/mL which exceeded the IC50 values (1.5 to 15 μg/mL for HIV and 5 to 25 μg/mL for HTLV). © 1998 John Wiley & Sons, Ltd.
ISSN:	0951-418X 1099-1573
DOI:	10.1002/(SICI)1099-1573(199808)12:5<367::AID-PTR301>3.0.CO;2-N