miRNAs as biomarkers of myocardial infarction: a step forward towards personalized medicine?
Highlights • Circulating levels of cardiac-enriched miRNAs are increased after myocardial infarction (MI). • Circulating miRNAs do not outperform troponins for the diagnosis of MI. • Some miRNAs or panels of miRNAs have a promising prognostic value after MI. • An emerging concept is that miRNAs may...
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| Veröffentlicht in: | Trends in molecular medicine 2014-12, Vol.20 (12), p.716-725 |
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| creator | Goretti, Emeline Wagner, Daniel R Devaux, Yvan |
| description | Highlights • Circulating levels of cardiac-enriched miRNAs are increased after myocardial infarction (MI). • Circulating miRNAs do not outperform troponins for the diagnosis of MI. • Some miRNAs or panels of miRNAs have a promising prognostic value after MI. • An emerging concept is that miRNAs may be used for personalized medicine. |
| doi_str_mv | 10.1016/j.molmed.2014.10.006 |
| format | Article |
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| ispartof | Trends in molecular medicine, 2014-12, Vol.20 (12), p.716-725 |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Animals biomarker Disease Models, Animal Gene Expression Regulation Genetic Markers Humans MicroRNAs - blood MicroRNAs - genetics miRNAs myocardial infarction Myocardial Infarction - diagnosis Myocardial Infarction - genetics Myocardial Infarction - therapy Pathology personalized medicine Precision Medicine - methods Prognosis therapeutic targets Treatment Outcome Troponin - genetics Troponin - metabolism |
| title | miRNAs as biomarkers of myocardial infarction: a step forward towards personalized medicine? |
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