Studies towards the synthesis of bielschowskysin. Construction of the highly functionalized bicyclo[3.2.0]heptane segment

A stereocontrolled approach for the construction of a highly functionalized bicyclo[3.2.0]heptane derivative embodying the bridged lactone present in the diterpene bielschowskysin is reported. The key step involves a stereoselective Cu(I)-catalyzed [2 + 2] photocycloaddition of a 1,6-diene embedded...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Organic & biomolecular chemistry 2015-02, Vol.13 (6), p.1846-1859
Hauptverfasser:	Jana, Anupam, Mondal, Sujit, Ghosh, Subrata
Format:	Artikel
Sprache:	eng
Schlagworte:	Bridged Bicyclo Compounds - chemistry Diterpenes - chemical synthesis Diterpenes - chemistry Heptanes - chemistry Molecular Conformation Stereoisomerism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	A stereocontrolled approach for the construction of a highly functionalized bicyclo[3.2.0]heptane derivative embodying the bridged lactone present in the diterpene bielschowskysin is reported. The key step involves a stereoselective Cu(I)-catalyzed [2 + 2] photocycloaddition of a 1,6-diene embedded in a sugar derivative.
ISSN:	1477-0520 1477-0539
DOI:	10.1039/c4ob02182g