One-step synthesis of magnetic hollow mesoporous silica (MHMS) nanospheres for drug delivery nanosystems via electrostatic self-assembly templated approach

In this work, yolk-shell structured magnetic hollow mesoporous silica (MHMS) nanospheres with controllable magnetic responsibility, high specific surface area, a huge cavity and ink-bottle type mesopores were successfully synthesized in one-step by an electrostatic self-assembly templated approach....

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Veröffentlicht in:	Chemical communications (Cambridge, England) England), 2015-02, Vol.51 (12), p.2357-2360
Hauptverfasser:	Liu, Fang, Wang, Jingnan, Cao, Qingyun, Deng, Haidong, Shao, Guang, Deng, David Y B, Zhou, Wuyi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis - drug effects Biocompatible Materials - chemical synthesis Biocompatible Materials - chemistry Biocompatible Materials - toxicity Drug Carriers - chemical synthesis Drug Carriers - chemistry Drug Carriers - toxicity Ferrosoferric Oxide - chemistry HEK293 Cells Hemolysis - drug effects Humans Magnetics Nanospheres - chemistry Nanospheres - toxicity Particle Size PC12 Cells Porosity Rats Silicon Dioxide - chemistry Static Electricity Surface Properties
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Beschreibung
Zusammenfassung:	In this work, yolk-shell structured magnetic hollow mesoporous silica (MHMS) nanospheres with controllable magnetic responsibility, high specific surface area, a huge cavity and ink-bottle type mesopores were successfully synthesized in one-step by an electrostatic self-assembly templated approach. The obtained MHMS nanospheres exhibited low cytotoxicity, excellent biocompatibility and potential application in the biomedical field.
ISSN:	1359-7345 1364-548X
DOI:	10.1039/c4cc08914f