Does the region of epileptogenicity influence the pattern of change in cortical excitability?

Highlights • We use transcranial magnetic stimulation to characterize cortical excitability in focal epilepsies. • Group TMS studies demonstrate that disturbances in cortical excitability are more confined to the affected hemisphere in drug naïve temporal lobe epilepsy. • Temporal lobe epilepsy can...

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Veröffentlicht in:	Clinical neurophysiology 2015-02, Vol.126 (2), p.249-256
Hauptverfasser:	Badawy, Radwa A.B, Vogrin, Simon J, Lai, Alan, Cook, Mark J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Cohort Studies Cortical excitability Epilepsies, Partial - diagnosis Epilepsies, Partial - physiopathology Epilepsy, Temporal Lobe - diagnosis Epilepsy, Temporal Lobe - physiopathology Evoked Potentials, Motor - physiology Female Focal epilepsy syndromes Humans Male Middle Aged Motor Cortex - physiopathology Neurology Seizures Transcranial magnetic stimulation Transcranial Magnetic Stimulation - methods Young Adult
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Zusammenfassung:	Highlights • We use transcranial magnetic stimulation to characterize cortical excitability in focal epilepsies. • Group TMS studies demonstrate that disturbances in cortical excitability are more confined to the affected hemisphere in drug naïve temporal lobe epilepsy. • Temporal lobe epilepsy can be distinguished from other focal epilepsies early at onset.
ISSN:	1388-2457 1872-8952
DOI:	10.1016/j.clinph.2014.05.029