General Last-Step Labeling of Biomolecule-Based Substrates by [12C], [13C], and [11C] Carbon Monoxide

Alkaloid-, steroid-, biotin-, carbohydrate-, nucleoside-, and peptide-based bioconjugates are easily labeled with CO by a last-step palladium-catalyzed carbonylation. The choice of the [12C], [13C], or [11C] isotope opens the way to a new class of potential tracers or ligands easily available for va...

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Veröffentlicht in:	Organic letters 2015-01, Vol.17 (2), p.354-357
Hauptverfasser:	Cornilleau, Thomas, Audrain, Hélène, Guillemet, Aude, Hermange, Philippe, Fouquet, Eric
Format:	Artikel
Sprache:	eng
Schlagworte:	Carbon Isotopes - chemistry Carbon Monoxide - chemistry Carbon Radioisotopes - chemistry Catalysis Immunologic Factors - chemistry Isotope Labeling - methods Molecular Structure
Online-Zugang:	Volltext
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