Widespread of ESBL- and carbapenemase GES-type genes on carbapenem-resistant Pseudomonas aeruginosa clinical isolates: a multicenter study in Mexican hospitals

Abstract The present work describes a prevalence of 36.2% of carbapenemases IMP-, VIM-, and GES-type on 124 imipenem-resistant Pseudomonas aeruginosa clinical isolates. The ESBL GES-19 and carbapenemase GES-20 genes were the most prevalent (84.4%) β-lactamases among imipenem-resistant P. aeruginosa...

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Veröffentlicht in:	Diagnostic microbiology and infectious disease 2015-02, Vol.81 (2), p.135-137
Hauptverfasser:	Garza-Ramos, Ulises, Barrios, Humberto, Reyna-Flores, Fernando, Tamayo-Legorreta, Elsa, Catalan-Najera, Juan C, Morfin-Otero, Rayo, Rodríguez-Noriega, Eduardo, Volkow, Patricia, Cornejo-Juarez, Patricia, González, Alejandra, Gaytan-Martinez, Jesus, del Rocío Gónzalez-Martínez, Marisela, Vazquez-Farias, Maria, Silva-Sanchez, Jesus
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology beta-Lactam Resistance beta-Lactamases - genetics Carbapenems - pharmacology Chromosomes, Bacterial ESBL Genes, Bacterial GES Hospitals Imipenem resistance IMP Infectious Disease Integrons Internal Medicine Mexico Pseudomonas aeruginosa - drug effects Pseudomonas aeruginosa - genetics Pseudomonas aeruginosa - isolation & purification Pseudomonas Infections - microbiology VIM
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Zusammenfassung:	Abstract The present work describes a prevalence of 36.2% of carbapenemases IMP-, VIM-, and GES-type on 124 imipenem-resistant Pseudomonas aeruginosa clinical isolates. The ESBL GES-19 and carbapenemase GES-20 genes were the most prevalent (84.4%) β-lactamases among imipenem-resistant P. aeruginosa clinical isolates in Mexico. These genes are chromosomal encoded on embedded class 1 integron arrays.
ISSN:	0732-8893 1879-0070
DOI:	10.1016/j.diagmicrobio.2014.09.029