Successful treatment of disseminated coccidioidomycosis with amphotericin B lipid complex

Coccidioidomycosis is endemic in regions of the Americas, but this infection may be encountered in travellers who return from an endemic region. A case is reported of a disseminated infection in a Hong Kong Chinese man, who was successfully treated with amphotericin B lipid complex (ABLC) after into...

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Veröffentlicht in:	The Journal of infection 1998, Vol.36 (1), p.113-115
Hauptverfasser:	Koehler, A.P., Cheng, A.F.B., Chu, K.C., Chan, C.H.S., Ho, A.S.S., Lyon, D.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Amphotericin B - therapeutic use Antifungal Agents - therapeutic use Biological and medical sciences Coccidioidomycosis Coccidioidomycosis - drug therapy Coccidioidomycosis - transmission Drug Combinations Human mycoses Humans Infectious diseases Male Medical sciences Mycoses Phosphatidylcholines - therapeutic use Phosphatidylglycerols - therapeutic use Treatment Outcome Tropical medicine Tropical mycoses
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Beschreibung
Zusammenfassung:	Coccidioidomycosis is endemic in regions of the Americas, but this infection may be encountered in travellers who return from an endemic region. A case is reported of a disseminated infection in a Hong Kong Chinese man, who was successfully treated with amphotericin B lipid complex (ABLC) after intolerance and toxicity precluded the use of other antifungal agents. Lipid-based formulations of amphotericin B merit further evaluation in the treatment of coccidioidomycosis and other systemic mycoses.
ISSN:	0163-4453 1532-2742
DOI:	10.1016/S0163-4453(98)93522-8