A functionalized fluorescent dendrimer as a pesticide nanocarrier: application in pest control
We report the delivery of a hydrophobic pesticide, thiamethoxam, by water-soluble nanosized cationic dendrimers that contain hydrophobic dendritic polyesters and peripheral amines, demonstrated by DLS, spectral analysis and ITC. The dendrimer-based nanocarrier can efficiently deliver the pesticide i...
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Veröffentlicht in: | Nanoscale 2015-01, Vol.7 (2), p.445-449 |
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creator | Liu, Xiaoxia He, Bicheng Xu, Zejun Yin, Meizhen Yang, Wantai Zhang, Huaijiang Cao, Jingjun Shen, Jie |
description | We report the delivery of a hydrophobic pesticide, thiamethoxam, by water-soluble nanosized cationic dendrimers that contain hydrophobic dendritic polyesters and peripheral amines, demonstrated by DLS, spectral analysis and ITC. The dendrimer-based nanocarrier can efficiently deliver the pesticide into the live cells and largely increase the cytotoxicity of the drug. |
doi_str_mv | 10.1039/c4nr05733c |
format | Article |
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The dendrimer-based nanocarrier can efficiently deliver the pesticide into the live cells and largely increase the cytotoxicity of the drug.</description><identifier>ISSN: 2040-3364</identifier><identifier>EISSN: 2040-3372</identifier><identifier>DOI: 10.1039/c4nr05733c</identifier><identifier>PMID: 25429649</identifier><language>eng</language><publisher>England</publisher><subject>Amines ; Amines - chemistry ; Animals ; Calorimetry ; Cationic ; Dendrimers ; Dendrimers - chemistry ; Drug Carriers - chemistry ; Drug delivery systems ; Hydrophobic and Hydrophilic Interactions ; Larva - drug effects ; Lepidoptera - drug effects ; Lepidoptera - growth & development ; Light ; Liver - metabolism ; Liver - pathology ; Nanostructure ; Nanostructures - chemistry ; Neonicotinoids ; Nitro Compounds - chemistry ; Nitro Compounds - metabolism ; Nitro Compounds - toxicity ; Oxazines - chemistry ; Oxazines - metabolism ; Oxazines - toxicity ; Pesticides ; Pesticides - chemistry ; Pesticides - metabolism ; Pesticides - toxicity ; Pests ; Polyesters - chemistry ; Scattering, Radiation ; Spectra ; Thiazoles - chemistry ; Thiazoles - metabolism ; Thiazoles - toxicity</subject><ispartof>Nanoscale, 2015-01, Vol.7 (2), p.445-449</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c402t-f5620856dd63712c2ed6f9af2f1bbd48c24582777052881c0cfdf7eff6bc3eb13</citedby><cites>FETCH-LOGICAL-c402t-f5620856dd63712c2ed6f9af2f1bbd48c24582777052881c0cfdf7eff6bc3eb13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25429649$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Liu, Xiaoxia</creatorcontrib><creatorcontrib>He, Bicheng</creatorcontrib><creatorcontrib>Xu, Zejun</creatorcontrib><creatorcontrib>Yin, Meizhen</creatorcontrib><creatorcontrib>Yang, Wantai</creatorcontrib><creatorcontrib>Zhang, Huaijiang</creatorcontrib><creatorcontrib>Cao, Jingjun</creatorcontrib><creatorcontrib>Shen, Jie</creatorcontrib><title>A functionalized fluorescent dendrimer as a pesticide nanocarrier: application in pest control</title><title>Nanoscale</title><addtitle>Nanoscale</addtitle><description>We report the delivery of a hydrophobic pesticide, thiamethoxam, by water-soluble nanosized cationic dendrimers that contain hydrophobic dendritic polyesters and peripheral amines, demonstrated by DLS, spectral analysis and ITC. The dendrimer-based nanocarrier can efficiently deliver the pesticide into the live cells and largely increase the cytotoxicity of the drug.</description><subject>Amines</subject><subject>Amines - chemistry</subject><subject>Animals</subject><subject>Calorimetry</subject><subject>Cationic</subject><subject>Dendrimers</subject><subject>Dendrimers - chemistry</subject><subject>Drug Carriers - chemistry</subject><subject>Drug delivery systems</subject><subject>Hydrophobic and Hydrophilic Interactions</subject><subject>Larva - drug effects</subject><subject>Lepidoptera - drug effects</subject><subject>Lepidoptera - growth & development</subject><subject>Light</subject><subject>Liver - metabolism</subject><subject>Liver - pathology</subject><subject>Nanostructure</subject><subject>Nanostructures - chemistry</subject><subject>Neonicotinoids</subject><subject>Nitro Compounds - chemistry</subject><subject>Nitro Compounds - metabolism</subject><subject>Nitro Compounds - toxicity</subject><subject>Oxazines - chemistry</subject><subject>Oxazines - metabolism</subject><subject>Oxazines - toxicity</subject><subject>Pesticides</subject><subject>Pesticides - chemistry</subject><subject>Pesticides - metabolism</subject><subject>Pesticides - toxicity</subject><subject>Pests</subject><subject>Polyesters - chemistry</subject><subject>Scattering, Radiation</subject><subject>Spectra</subject><subject>Thiazoles - chemistry</subject><subject>Thiazoles - metabolism</subject><subject>Thiazoles - toxicity</subject><issn>2040-3364</issn><issn>2040-3372</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkMtKxDAUQIMozji68QMkSxFG807rbii-YFAQ3VrSPCDSSWrSLvTr7Tyctat7F4fDvQeAc4yuMaLljWYhIS4p1QdgShBDc0olOdzvgk3ASc6fCImSCnoMJoQzUgpWTsHHAroh6N7HoFr_Yw107RCTzdqGHhobTPIrm6DKUMHO5t5rbywMKkStUvI23ULVda3Xau2APmwoqGPoU2xPwZFTbbZnuzkD7_d3b9XjfPny8FQtlnPNEOnnjguCCi6MEVRiook1wpXKEYebxrBCE8YLIqVEnBQF1kg746R1TjSa2gbTGbjcersUv4bxgHrlxxfaVgUbh1xjwTGjDDH2D5RKzkpJxIhebVGdYs7Juroba6j0XWNUr9PXFXt-3aSvRvhi5x2alTV79K81_QWYq3-j</recordid><startdate>20150114</startdate><enddate>20150114</enddate><creator>Liu, Xiaoxia</creator><creator>He, Bicheng</creator><creator>Xu, Zejun</creator><creator>Yin, Meizhen</creator><creator>Yang, Wantai</creator><creator>Zhang, Huaijiang</creator><creator>Cao, Jingjun</creator><creator>Shen, Jie</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7SR</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>F28</scope><scope>FR3</scope><scope>JG9</scope><scope>L7M</scope></search><sort><creationdate>20150114</creationdate><title>A functionalized fluorescent dendrimer as a pesticide nanocarrier: application in pest control</title><author>Liu, Xiaoxia ; He, Bicheng ; Xu, Zejun ; Yin, Meizhen ; Yang, Wantai ; Zhang, Huaijiang ; Cao, Jingjun ; Shen, Jie</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c402t-f5620856dd63712c2ed6f9af2f1bbd48c24582777052881c0cfdf7eff6bc3eb13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Amines</topic><topic>Amines - chemistry</topic><topic>Animals</topic><topic>Calorimetry</topic><topic>Cationic</topic><topic>Dendrimers</topic><topic>Dendrimers - chemistry</topic><topic>Drug Carriers - chemistry</topic><topic>Drug delivery systems</topic><topic>Hydrophobic and Hydrophilic Interactions</topic><topic>Larva - drug effects</topic><topic>Lepidoptera - drug effects</topic><topic>Lepidoptera - growth & development</topic><topic>Light</topic><topic>Liver - metabolism</topic><topic>Liver - pathology</topic><topic>Nanostructure</topic><topic>Nanostructures - chemistry</topic><topic>Neonicotinoids</topic><topic>Nitro Compounds - chemistry</topic><topic>Nitro Compounds - metabolism</topic><topic>Nitro Compounds - toxicity</topic><topic>Oxazines - chemistry</topic><topic>Oxazines - metabolism</topic><topic>Oxazines - toxicity</topic><topic>Pesticides</topic><topic>Pesticides - chemistry</topic><topic>Pesticides - metabolism</topic><topic>Pesticides - toxicity</topic><topic>Pests</topic><topic>Polyesters - chemistry</topic><topic>Scattering, Radiation</topic><topic>Spectra</topic><topic>Thiazoles - chemistry</topic><topic>Thiazoles - metabolism</topic><topic>Thiazoles - toxicity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Liu, Xiaoxia</creatorcontrib><creatorcontrib>He, Bicheng</creatorcontrib><creatorcontrib>Xu, Zejun</creatorcontrib><creatorcontrib>Yin, Meizhen</creatorcontrib><creatorcontrib>Yang, Wantai</creatorcontrib><creatorcontrib>Zhang, Huaijiang</creatorcontrib><creatorcontrib>Cao, Jingjun</creatorcontrib><creatorcontrib>Shen, Jie</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Engineered Materials Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><collection>Materials Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>Nanoscale</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Liu, Xiaoxia</au><au>He, Bicheng</au><au>Xu, Zejun</au><au>Yin, Meizhen</au><au>Yang, Wantai</au><au>Zhang, Huaijiang</au><au>Cao, Jingjun</au><au>Shen, Jie</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A functionalized fluorescent dendrimer as a pesticide nanocarrier: application in pest control</atitle><jtitle>Nanoscale</jtitle><addtitle>Nanoscale</addtitle><date>2015-01-14</date><risdate>2015</risdate><volume>7</volume><issue>2</issue><spage>445</spage><epage>449</epage><pages>445-449</pages><issn>2040-3364</issn><eissn>2040-3372</eissn><abstract>We report the delivery of a hydrophobic pesticide, thiamethoxam, by water-soluble nanosized cationic dendrimers that contain hydrophobic dendritic polyesters and peripheral amines, demonstrated by DLS, spectral analysis and ITC. 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subjects | Amines Amines - chemistry Animals Calorimetry Cationic Dendrimers Dendrimers - chemistry Drug Carriers - chemistry Drug delivery systems Hydrophobic and Hydrophilic Interactions Larva - drug effects Lepidoptera - drug effects Lepidoptera - growth & development Light Liver - metabolism Liver - pathology Nanostructure Nanostructures - chemistry Neonicotinoids Nitro Compounds - chemistry Nitro Compounds - metabolism Nitro Compounds - toxicity Oxazines - chemistry Oxazines - metabolism Oxazines - toxicity Pesticides Pesticides - chemistry Pesticides - metabolism Pesticides - toxicity Pests Polyesters - chemistry Scattering, Radiation Spectra Thiazoles - chemistry Thiazoles - metabolism Thiazoles - toxicity |
title | A functionalized fluorescent dendrimer as a pesticide nanocarrier: application in pest control |
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