Kinetic resolution of racemic (cyclohexyl)(geranyl)acetic acid

Kinetic resolution of racemic (cyclohexyl)(geranyl)acetic acid

A kinetic resolution of racemic (cyclohexyl)(geranyl)acetic acid, the active ingredient of wound-curing medication Cygerol, to (S)- and (R)-enantiomers was achieved by diastereoselective esterification with (S)- or (R)-BINOL.

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Veröffentlicht in:Mendeleev communications 2014-09, Vol.24 (5), p.257-259
Hauptverfasser: Zlotin, Sergei G., Kryshtal, Galina V., Zhdankina, Galina M., Sukhanova, Anna A., Kucherenko, Alexander S., Smirnov, Boris B., Tartakovsky, Vladimir A.
Format: Artikel
Sprache:eng
Schlagworte:
Esterification
Ingredients
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Zusammenfassung:A kinetic resolution of racemic (cyclohexyl)(geranyl)acetic acid, the active ingredient of wound-curing medication Cygerol, to (S)- and (R)-enantiomers was achieved by diastereoselective esterification with (S)- or (R)-BINOL.
ISSN:0959-9436
DOI:10.1016/j.mencom.2014.09.002