Prenatal caffeine ingestion induces aberrant DNA methylation and histone acetylation of steroidogenic factor 1 and inhibits fetal adrenal steroidogenesis
Highlights • Prenatal caffeine ingestion inhibits corticosterone production in fetal adrenal. • Prenatal caffeine ingestion inhibits SF-1 and steroidogenic enzymes expression. • Prenatal caffeine ingestion induces abberant DNA methylation of SF-1 promoter. • Prenatal caffeine ingestion induces abber...
Gespeichert in:
| Veröffentlicht in: | Toxicology (Amsterdam) 2014-07, Vol.321, p.53-61 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 61 |
|---|---|
| container_issue | |
| container_start_page | 53 |
| container_title | Toxicology (Amsterdam) |
| container_volume | 321 |
| creator | Ping, Jie Wang, Jian-fei Liu, Lian Yan, You-e Liu, Fang Lei, You-ying Wang, Hui |
| description | Highlights • Prenatal caffeine ingestion inhibits corticosterone production in fetal adrenal. • Prenatal caffeine ingestion inhibits SF-1 and steroidogenic enzymes expression. • Prenatal caffeine ingestion induces abberant DNA methylation of SF-1 promoter. • Prenatal caffeine ingestion induces abberant histone acetylation of SF-1 promoter. |
| doi_str_mv | 10.1016/j.tox.2014.03.011 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1651417029</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0300483X14000675</els_id><sourcerecordid>1647002971</sourcerecordid><originalsourceid>FETCH-LOGICAL-c474t-3e2e1d49b6d431e31b733542c16ba621cbeead79c8ce71084a3dcd13f89ced933</originalsourceid><addsrcrecordid>eNqNktFqFDEUhoModlt9AG8kl97MmDPJTGYQhFKtCkUFFbwLmeRMN-ts0iZZcR_FtzXTbUW8EK8Swv-fnP98h5AnwGpg0D3f1Dn8qBsGoma8ZgD3yAp6OVQc-vY-WTHOWCV6_vWIHKe0YYw1XHQPyVEjJMi2bVbk58eIXmc9U6OnCZ1H6vwlpuyCLze7M5ioHjFG7TN99f6UbjGv97O-EWhv6dqlHIpNG8x372GiKWMMzoZL9M7QSZscIoUbh_NrN7qc6ITLx9ouLcx_OjC59Ig8mPSc8PHteUK-nL_-fPa2uvjw5t3Z6UVlhBS54tggWDGMnRUckMMoOW9FY6AbddeAGRG1lYPpDUpgvdDcGgt86geDduD8hDw71L2K4XpXkqutSwbnWXsMu6Sga0GAZM3wH1Ihy4wHCUUKB6mJIaWIk7qKbqvjXgFTCzy1UQWeWuApxlWBVzxPb8vvxi3a3447WkXw4iDAMo_vDqNKxqEvOVxEk5UN7p_lX_7lNrMrcPT8DfeYNmEXC4aSQqVGMfVp2Z5leUCUxelky38B2mXCzA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1647002971</pqid></control><display><type>article</type><title>Prenatal caffeine ingestion induces aberrant DNA methylation and histone acetylation of steroidogenic factor 1 and inhibits fetal adrenal steroidogenesis</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Ping, Jie ; Wang, Jian-fei ; Liu, Lian ; Yan, You-e ; Liu, Fang ; Lei, You-ying ; Wang, Hui</creator><creatorcontrib>Ping, Jie ; Wang, Jian-fei ; Liu, Lian ; Yan, You-e ; Liu, Fang ; Lei, You-ying ; Wang, Hui</creatorcontrib><description>Highlights • Prenatal caffeine ingestion inhibits corticosterone production in fetal adrenal. • Prenatal caffeine ingestion inhibits SF-1 and steroidogenic enzymes expression. • Prenatal caffeine ingestion induces abberant DNA methylation of SF-1 promoter. • Prenatal caffeine ingestion induces abberant histone acetylation of SF-1 promoter.</description><identifier>ISSN: 0300-483X</identifier><identifier>EISSN: 1879-3185</identifier><identifier>DOI: 10.1016/j.tox.2014.03.011</identifier><identifier>PMID: 24717552</identifier><language>eng</language><publisher>Ireland: Elsevier Ireland Ltd</publisher><subject>Acetylation ; Adrenal Glands - drug effects ; Adrenal Glands - embryology ; Adrenal Glands - metabolism ; Animals ; Anti-Inflammatory Agents - pharmacology ; Caffeine ; Caffeine - toxicity ; Central Nervous System Stimulants - toxicity ; Chromatin Immunoprecipitation ; Corticosterone - pharmacology ; Deoxyribonucleic acid ; DNA methylation ; DNA Methylation - drug effects ; Emergency ; Enzymes ; Epigenesis, Genetic - drug effects ; Female ; Fetal adrenal ; Gene expression ; Histone acetylation ; Histones ; Histones - metabolism ; Immunohistochemistry ; Ingestion ; Intrauterine growth retardation (IUGR) ; Methylation ; Pregnancy ; Rats ; Rats, Wistar ; Real-Time Polymerase Chain Reaction ; RNA ; Steroidogenic Factor 1 - metabolism ; Steroidogenic factor-1 (SF-1) ; Steroids - biosynthesis</subject><ispartof>Toxicology (Amsterdam), 2014-07, Vol.321, p.53-61</ispartof><rights>Elsevier Ireland Ltd</rights><rights>2014 Elsevier Ireland Ltd</rights><rights>Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c474t-3e2e1d49b6d431e31b733542c16ba621cbeead79c8ce71084a3dcd13f89ced933</citedby><cites>FETCH-LOGICAL-c474t-3e2e1d49b6d431e31b733542c16ba621cbeead79c8ce71084a3dcd13f89ced933</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0300483X14000675$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24717552$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ping, Jie</creatorcontrib><creatorcontrib>Wang, Jian-fei</creatorcontrib><creatorcontrib>Liu, Lian</creatorcontrib><creatorcontrib>Yan, You-e</creatorcontrib><creatorcontrib>Liu, Fang</creatorcontrib><creatorcontrib>Lei, You-ying</creatorcontrib><creatorcontrib>Wang, Hui</creatorcontrib><title>Prenatal caffeine ingestion induces aberrant DNA methylation and histone acetylation of steroidogenic factor 1 and inhibits fetal adrenal steroidogenesis</title><title>Toxicology (Amsterdam)</title><addtitle>Toxicology</addtitle><description>Highlights • Prenatal caffeine ingestion inhibits corticosterone production in fetal adrenal. • Prenatal caffeine ingestion inhibits SF-1 and steroidogenic enzymes expression. • Prenatal caffeine ingestion induces abberant DNA methylation of SF-1 promoter. • Prenatal caffeine ingestion induces abberant histone acetylation of SF-1 promoter.</description><subject>Acetylation</subject><subject>Adrenal Glands - drug effects</subject><subject>Adrenal Glands - embryology</subject><subject>Adrenal Glands - metabolism</subject><subject>Animals</subject><subject>Anti-Inflammatory Agents - pharmacology</subject><subject>Caffeine</subject><subject>Caffeine - toxicity</subject><subject>Central Nervous System Stimulants - toxicity</subject><subject>Chromatin Immunoprecipitation</subject><subject>Corticosterone - pharmacology</subject><subject>Deoxyribonucleic acid</subject><subject>DNA methylation</subject><subject>DNA Methylation - drug effects</subject><subject>Emergency</subject><subject>Enzymes</subject><subject>Epigenesis, Genetic - drug effects</subject><subject>Female</subject><subject>Fetal adrenal</subject><subject>Gene expression</subject><subject>Histone acetylation</subject><subject>Histones</subject><subject>Histones - metabolism</subject><subject>Immunohistochemistry</subject><subject>Ingestion</subject><subject>Intrauterine growth retardation (IUGR)</subject><subject>Methylation</subject><subject>Pregnancy</subject><subject>Rats</subject><subject>Rats, Wistar</subject><subject>Real-Time Polymerase Chain Reaction</subject><subject>RNA</subject><subject>Steroidogenic Factor 1 - metabolism</subject><subject>Steroidogenic factor-1 (SF-1)</subject><subject>Steroids - biosynthesis</subject><issn>0300-483X</issn><issn>1879-3185</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNktFqFDEUhoModlt9AG8kl97MmDPJTGYQhFKtCkUFFbwLmeRMN-ts0iZZcR_FtzXTbUW8EK8Swv-fnP98h5AnwGpg0D3f1Dn8qBsGoma8ZgD3yAp6OVQc-vY-WTHOWCV6_vWIHKe0YYw1XHQPyVEjJMi2bVbk58eIXmc9U6OnCZ1H6vwlpuyCLze7M5ioHjFG7TN99f6UbjGv97O-EWhv6dqlHIpNG8x372GiKWMMzoZL9M7QSZscIoUbh_NrN7qc6ITLx9ouLcx_OjC59Ig8mPSc8PHteUK-nL_-fPa2uvjw5t3Z6UVlhBS54tggWDGMnRUckMMoOW9FY6AbddeAGRG1lYPpDUpgvdDcGgt86geDduD8hDw71L2K4XpXkqutSwbnWXsMu6Sga0GAZM3wH1Ihy4wHCUUKB6mJIaWIk7qKbqvjXgFTCzy1UQWeWuApxlWBVzxPb8vvxi3a3447WkXw4iDAMo_vDqNKxqEvOVxEk5UN7p_lX_7lNrMrcPT8DfeYNmEXC4aSQqVGMfVp2Z5leUCUxelky38B2mXCzA</recordid><startdate>20140703</startdate><enddate>20140703</enddate><creator>Ping, Jie</creator><creator>Wang, Jian-fei</creator><creator>Liu, Lian</creator><creator>Yan, You-e</creator><creator>Liu, Fang</creator><creator>Lei, You-ying</creator><creator>Wang, Hui</creator><general>Elsevier Ireland Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TM</scope><scope>7U7</scope><scope>C1K</scope><scope>8FD</scope><scope>FR3</scope><scope>KR7</scope></search><sort><creationdate>20140703</creationdate><title>Prenatal caffeine ingestion induces aberrant DNA methylation and histone acetylation of steroidogenic factor 1 and inhibits fetal adrenal steroidogenesis</title><author>Ping, Jie ; Wang, Jian-fei ; Liu, Lian ; Yan, You-e ; Liu, Fang ; Lei, You-ying ; Wang, Hui</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c474t-3e2e1d49b6d431e31b733542c16ba621cbeead79c8ce71084a3dcd13f89ced933</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Acetylation</topic><topic>Adrenal Glands - drug effects</topic><topic>Adrenal Glands - embryology</topic><topic>Adrenal Glands - metabolism</topic><topic>Animals</topic><topic>Anti-Inflammatory Agents - pharmacology</topic><topic>Caffeine</topic><topic>Caffeine - toxicity</topic><topic>Central Nervous System Stimulants - toxicity</topic><topic>Chromatin Immunoprecipitation</topic><topic>Corticosterone - pharmacology</topic><topic>Deoxyribonucleic acid</topic><topic>DNA methylation</topic><topic>DNA Methylation - drug effects</topic><topic>Emergency</topic><topic>Enzymes</topic><topic>Epigenesis, Genetic - drug effects</topic><topic>Female</topic><topic>Fetal adrenal</topic><topic>Gene expression</topic><topic>Histone acetylation</topic><topic>Histones</topic><topic>Histones - metabolism</topic><topic>Immunohistochemistry</topic><topic>Ingestion</topic><topic>Intrauterine growth retardation (IUGR)</topic><topic>Methylation</topic><topic>Pregnancy</topic><topic>Rats</topic><topic>Rats, Wistar</topic><topic>Real-Time Polymerase Chain Reaction</topic><topic>RNA</topic><topic>Steroidogenic Factor 1 - metabolism</topic><topic>Steroidogenic factor-1 (SF-1)</topic><topic>Steroids - biosynthesis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ping, Jie</creatorcontrib><creatorcontrib>Wang, Jian-fei</creatorcontrib><creatorcontrib>Liu, Lian</creatorcontrib><creatorcontrib>Yan, You-e</creatorcontrib><creatorcontrib>Liu, Fang</creatorcontrib><creatorcontrib>Lei, You-ying</creatorcontrib><creatorcontrib>Wang, Hui</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Nucleic Acids Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Civil Engineering Abstracts</collection><jtitle>Toxicology (Amsterdam)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ping, Jie</au><au>Wang, Jian-fei</au><au>Liu, Lian</au><au>Yan, You-e</au><au>Liu, Fang</au><au>Lei, You-ying</au><au>Wang, Hui</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prenatal caffeine ingestion induces aberrant DNA methylation and histone acetylation of steroidogenic factor 1 and inhibits fetal adrenal steroidogenesis</atitle><jtitle>Toxicology (Amsterdam)</jtitle><addtitle>Toxicology</addtitle><date>2014-07-03</date><risdate>2014</risdate><volume>321</volume><spage>53</spage><epage>61</epage><pages>53-61</pages><issn>0300-483X</issn><eissn>1879-3185</eissn><abstract>Highlights • Prenatal caffeine ingestion inhibits corticosterone production in fetal adrenal. • Prenatal caffeine ingestion inhibits SF-1 and steroidogenic enzymes expression. • Prenatal caffeine ingestion induces abberant DNA methylation of SF-1 promoter. • Prenatal caffeine ingestion induces abberant histone acetylation of SF-1 promoter.</abstract><cop>Ireland</cop><pub>Elsevier Ireland Ltd</pub><pmid>24717552</pmid><doi>10.1016/j.tox.2014.03.011</doi><tpages>9</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0300-483X |
| ispartof | Toxicology (Amsterdam), 2014-07, Vol.321, p.53-61 |
| issn | 0300-483X 1879-3185 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1651417029 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Acetylation Adrenal Glands - drug effects Adrenal Glands - embryology Adrenal Glands - metabolism Animals Anti-Inflammatory Agents - pharmacology Caffeine Caffeine - toxicity Central Nervous System Stimulants - toxicity Chromatin Immunoprecipitation Corticosterone - pharmacology Deoxyribonucleic acid DNA methylation DNA Methylation - drug effects Emergency Enzymes Epigenesis, Genetic - drug effects Female Fetal adrenal Gene expression Histone acetylation Histones Histones - metabolism Immunohistochemistry Ingestion Intrauterine growth retardation (IUGR) Methylation Pregnancy Rats Rats, Wistar Real-Time Polymerase Chain Reaction RNA Steroidogenic Factor 1 - metabolism Steroidogenic factor-1 (SF-1) Steroids - biosynthesis |
| title | Prenatal caffeine ingestion induces aberrant DNA methylation and histone acetylation of steroidogenic factor 1 and inhibits fetal adrenal steroidogenesis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-29T02%3A16%3A35IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Prenatal%20caffeine%20ingestion%20induces%20aberrant%20DNA%20methylation%20and%20histone%20acetylation%20of%20steroidogenic%20factor%201%20and%20inhibits%20fetal%20adrenal%20steroidogenesis&rft.jtitle=Toxicology%20(Amsterdam)&rft.au=Ping,%20Jie&rft.date=2014-07-03&rft.volume=321&rft.spage=53&rft.epage=61&rft.pages=53-61&rft.issn=0300-483X&rft.eissn=1879-3185&rft_id=info:doi/10.1016/j.tox.2014.03.011&rft_dat=%3Cproquest_cross%3E1647002971%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1647002971&rft_id=info:pmid/24717552&rft_els_id=S0300483X14000675&rfr_iscdi=true |