Temporal control of neural progenitors: TGF-β switches the clock forward

Little is known about how vertebrate neural progenitors in a given spatial domain change their identity over time. In this issue of Neuron, Dias et al. (2014) discover that hindbrain progenitors switch their output in response to TGF-β signaling.

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Bibliographische Detailangaben
Veröffentlicht in:	Neuron (Cambridge, Mass.) Mass.), 2014-12, Vol.84 (5), p.885-888
Hauptverfasser:	Mattar, Pierre, Cayouette, Michel
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Central Nervous System - cytology Female Gene Expression Regulation, Developmental - physiology Neural Stem Cells - physiology Neurogenesis - physiology Pregnancy Protein-Serine-Threonine Kinases - metabolism Receptors, Transforming Growth Factor beta - metabolism Signal Transduction - physiology
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Beschreibung
Zusammenfassung:	Little is known about how vertebrate neural progenitors in a given spatial domain change their identity over time. In this issue of Neuron, Dias et al. (2014) discover that hindbrain progenitors switch their output in response to TGF-β signaling.
ISSN:	0896-6273 1097-4199
DOI:	10.1016/j.neuron.2014.11.013