Looking at LncRNAs with the Ribozyme Toolkit

Looking at LncRNAs with the Ribozyme Toolkit

A diverse population of large RNA molecules controls every aspect of cellular function, and yet we know very little about their molecular structures. However, robust technologies developed for visualizing ribozymes and riboswitches, together with new approaches for mapping RNA inside cells, provide...

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Veröffentlicht in:Molecular cell 2014-10, Vol.56 (1), p.13-17
1. Verfasser: Pyle, Anna Marie
Format: Artikel
Sprache:eng
Schlagworte:
Gene Expression Regulation
Models, Genetic
Nucleic Acid Conformation
RNA Folding
RNA, Catalytic - chemistry
RNA, Catalytic - physiology
RNA, Long Noncoding - chemistry
RNA, Long Noncoding - physiology
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Zusammenfassung:A diverse population of large RNA molecules controls every aspect of cellular function, and yet we know very little about their molecular structures. However, robust technologies developed for visualizing ribozymes and riboswitches, together with new approaches for mapping RNA inside cells, provide the foundation for visualizing the structures of long noncoding RNAs, mRNAs, and viral RNAs, thereby facilitating new mechanistic insights.
ISSN:1097-2765
1097-4164
DOI:10.1016/j.molcel.2014.08.025