Gallium-Catalyzed Reductive Chlorination of Carboxylic Acids with Copper(II) Chloride

Gallium-Catalyzed Reductive Chlorination of Carboxylic Acids with Copper(II) Chloride

Described herein is the direct chlorination of carboxylic acids using copper(II) chloride via a gallium(III)-catalyzed reduction in the presence of a hydrosiloxane. During this reductive chlorination, the counteranions of CuCl2 functioned as a chloride source.

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Veröffentlicht in:Journal of organic chemistry 2014-11, Vol.79 (21), p.10619-10623
Hauptverfasser: Sakai, Norio, Nakajima, Takumi, Yoneda, Shinichiro, Konakahara, Takeo, Ogiwara, Yohei
Format: Artikel
Sprache:eng
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Zusammenfassung:Described herein is the direct chlorination of carboxylic acids using copper(II) chloride via a gallium(III)-catalyzed reduction in the presence of a hydrosiloxane. During this reductive chlorination, the counteranions of CuCl2 functioned as a chloride source.
ISSN:0022-3263
1520-6904
DOI:10.1021/jo501912v