Recent research trends of radio-frequency biosensors for biomolecular detection

This article reviews radio-frequency (RF) biosensors based on passive and/or active devices and circuits. In particular, we focus on RF biosensors designed for detection of various biomolecules such as biotin–streptavidin, DNA hybridization, IgG, and glucose. The performance of these biosensors has been enhanced by the introduction of various sensing schemes with diverse nanomaterials (e.g., carbon nanotubes, graphene oxide, magnetic and gold nanoparticles, etc.). In addition, the RF biosensing platforms that can be associated with an RF active system are discussed. Finally, the challenges of RF biosensors are presented and suggestions are made for their future direction and prospects. •This paper reviews RF biosensors for biomolecular detection.•The representative RF biosensors are introduced and analyzed.•The recently developed RF biosensors are estimated and analyzed in detail.•The challenges of RF biosensors and their future direction are presented.