Factors predicting recurrence in patients with Siewert type II carcinoma treated with curative resection

To evaluate the recurrence risk for Siewert type II esophagogastric junction carcinoma treated with curative resection. We retrospectively analyzed clinicopathological and recurrence-free survival (RFS) data of 52 patients after curative resection for Siewert type II carcinoma focusing on the role o...

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Veröffentlicht in:	Anticancer research 2015-01, Vol.35 (1), p.505-509
Hauptverfasser:	Fukuchi, Minoru, Mochiki, Erito, Suzuki, Okihide, Ishiguro, Toru, Sobajima, Jun, Onozawa, Hisashi, Imaizumi, Hideko, Shibata, Kazue, Saito, Kana, Naitoh, Hiroshi, Kumagai, Youichi, Ishibashi, Keiichiro, Ishida, Hideyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - mortality Adenocarcinoma - secondary Adenocarcinoma - surgery Adult Aged Aged, 80 and over Disease-Free Survival Esophageal Neoplasms - mortality Esophageal Neoplasms - pathology Esophageal Neoplasms - surgery Esophagogastric Junction - pathology Esophagogastric Junction - surgery Female Humans Kaplan-Meier Estimate Lymphatic Metastasis Male Middle Aged Multivariate Analysis Neoplasm Recurrence, Local - mortality Neoplasm Recurrence, Local - prevention & control Proportional Hazards Models Retrospective Studies Risk Factors Stomach Neoplasms - mortality Stomach Neoplasms - pathology Stomach Neoplasms - surgery
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Zusammenfassung:	To evaluate the recurrence risk for Siewert type II esophagogastric junction carcinoma treated with curative resection. We retrospectively analyzed clinicopathological and recurrence-free survival (RFS) data of 52 patients after curative resection for Siewert type II carcinoma focusing on the role of lymph node metastasis around the greater curvature or parapyloric area. Recurrence was observed in 21 (40%) patients; the median time-to-recurrence was 11 months (range=3-33 months). According to multivariate Cox proportional hazard regression analysis, involvement of nodes no. 4sa, 4sb, 4d, 5 and/or 6 (odds ratio (OR)=6.62; 95% confidence interval (CI)=1.27-41.1; p=0.04) and younger age (OR=2.10; 95% CI=1.25-3.82; p
ISSN:	1791-7530