Rare presentation of secondary cutaneous involvement by splenic marginal zone lymphoma: report of a case and review of the literature

Cutaneous lymphomas encompass a broad spectrum of malignancies, including both primary and secondary cutaneous lymphomas. Determining the exact subtype of cutaneous lymphoma offers prognostic importance and directs therapeutic decisions. We describe the case of a 67-year-old woman with cutaneous inv...

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Veröffentlicht in:	The American journal of dermatopathology 2015-01, Vol.37 (1), p.e1-e4
Hauptverfasser:	Cohen, Jeffrey M, Nazarian, Rosalynn M, Ferry, Judith A, Takvorian, Ronald W, Carter, Joi B
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antibodies, Monoclonal, Murine-Derived - administration & dosage Antineoplastic Combined Chemotherapy Protocols - therapeutic use Bendamustine Hydrochloride Biomarkers, Tumor - analysis Biopsy Female Humans Immunohistochemistry Lymphoma, B-Cell, Marginal Zone - chemistry Lymphoma, B-Cell, Marginal Zone - drug therapy Lymphoma, B-Cell, Marginal Zone - pathology Nitrogen Mustard Compounds - administration & dosage Predictive Value of Tests Remission Induction Rituximab Skin Neoplasms - chemistry Skin Neoplasms - drug therapy Skin Neoplasms - secondary Splenic Neoplasms - chemistry Splenic Neoplasms - drug therapy Splenic Neoplasms - pathology Time Factors Treatment Outcome
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Zusammenfassung:	Cutaneous lymphomas encompass a broad spectrum of malignancies, including both primary and secondary cutaneous lymphomas. Determining the exact subtype of cutaneous lymphoma offers prognostic importance and directs therapeutic decisions. We describe the case of a 67-year-old woman with cutaneous involvement of splenic marginal zone lymphoma successfully treated with rituximab and bendamustine. We discuss the diagnostic work-up, including the histopathologic findings and treatment of this disease.
ISSN:	0193-1091 1533-0311
DOI:	10.1097/DAD.0000000000000055