Risk Factors of Cerebral Microbleeds in Strictly Deep or Lobar Brain Regions Differed

Risk Factors of Cerebral Microbleeds in Strictly Deep or Lobar Brain Regions Differed

Background T2*-weighted gradient echo magnetic resonance imaging is sensitive in detecting cerebral microbleeds (MBs), but there are few reports on the risk factors of MBs in different brain regions. Therefore, we aimed to investigate whether the risk factors associated with the presence of MBs in s...

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Veröffentlicht in:Journal of stroke and cerebrovascular diseases 2015-01, Vol.24 (1), p.24-30
Hauptverfasser: Zhang, Changqing, MD, Li, Zixiao, MD, Wang, Yilong, MD, Zhao, Xingquan, MD, Wang, Chunxue, MD, Liu, Liping, MD, Pu, Yuehua, MD, Zou, Xinying, MD, Pan, Yuesong, MD, Du, Wanliang, MD, Jing, Jing, MD, Wang, Dongxue, MD, Luo, Yang, MD, Wong, Ka Sing, MD, Wang, Yongjun, MD
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Age Factors
Aged
Aged, 80 and over
Brain - pathology
Brain Ischemia - complications
Brain Ischemia - pathology
Cardiovascular
cerebral small vessel diseases
Female
Humans
Intracranial Hemorrhages - complications
Intracranial Hemorrhages - pathology
magnetic resonance imaging
Male
Microbleeds
Middle Aged
Neurology
Risk Factors
Stroke - complications
Stroke - pathology
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Zusammenfassung:Background T2*-weighted gradient echo magnetic resonance imaging is sensitive in detecting cerebral microbleeds (MBs), but there are few reports on the risk factors of MBs in different brain regions. Therefore, we aimed to investigate whether the risk factors associated with the presence of MBs in strictly deep or lobar brain regions were different. Methods This study consisted of 696 consecutive acute ischemic stroke patients from 6 hospitals in the Chinese IntraCranial AtheroSclerosis Study. We evaluated the number and location of MBs, severity of lacune and leukoaraiosis (LA), and etiologic subtype of ischemic stroke. Multivariable logistic regression was used to analyze risk factors of MBs in different brain regions. Results Among 696 acute ischemic stroke patients, 162 patients (23.3%) had MBs. Of them, 62 patients had strictly deep brain MBs, 49 patients had strictly lobar MBs. There was a significant correlation between the number of MBs, the number of lacune, and the severity of LA ( P  
ISSN:1052-3057
1532-8511
DOI:10.1016/j.jstrokecerebrovasdis.2014.07.041