Brain FDG PET and the diagnosis of dementia

We review the role of brain FDG PET in the diagnosis of Alzheimer disease, frontotemporal dementia, dementia with Lewy bodies, and vascular dementia. Characteristic spatial patterns of brain metabolism on FDG PET can help differentiate various subtypes of dementia. In patients with different subtype...

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Veröffentlicht in:	American journal of roentgenology (1976) 2015-01, Vol.204 (1), p.W76-W85
Hauptverfasser:	Shivamurthy, Veeresh K N, Tahari, Abdel K, Marcus, Charles, Subramaniam, Rathan M
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Brain - diagnostic imaging Brain - metabolism Dementia - diagnostic imaging Dementia - metabolism Female Fluorodeoxyglucose F18 - pharmacokinetics Humans Male Middle Aged Molecular Imaging - methods Positron-Emission Tomography - methods Radiopharmaceuticals - pharmacokinetics
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Zusammenfassung:	We review the role of brain FDG PET in the diagnosis of Alzheimer disease, frontotemporal dementia, dementia with Lewy bodies, and vascular dementia. Characteristic spatial patterns of brain metabolism on FDG PET can help differentiate various subtypes of dementia. In patients with different subtypes of dementia, FDG PET/CT shows distinct spatial patterns of metabolism in the brain and can help clinicians to make a reasonably accurate and early diagnosis for appropriate management or prognosis.
ISSN:	0361-803X 1546-3141
DOI:	10.2214/AJR.13.12363