HHV-6-positivity in diseases with demyelination

Highlights • We studied patients who had HHV-6-reactive OCBs in their CSF. • Most of the patients with HHV-6-reactivity had a demyelinating disease, mostly MS. • Studied patients had significantly more OCBs and were younger than the others.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of clinical virology 2014-10, Vol.61 (2), p.216-219
Hauptverfasser:	Pietiläinen-Nicklén, Jenna, Virtanen, Jussi O, Uotila, Lasse, Salonen, Oili, Färkkilä, Markus, Koskiniemi, Marjaleena
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Allergy and Immunology Blood - immunology Cerebrospinal Fluid - immunology Demyelinating disease Demyelinating Diseases - etiology Demyelinating Diseases - immunology Demyelinating Diseases - pathology Female Finland Head - diagnostic imaging Herpesvirus 6, Human - immunology Human herpesvirus 6 Humans Infectious Disease Isoelectric focusing Magnetic Resonance Imaging Male Multiple sclerosis Oligoclonal bands Oligoclonal Bands - cerebrospinal fluid Radiography Roseolovirus Infections - diagnosis Roseolovirus Infections - immunology Roseolovirus Infections - pathology
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Beschreibung
Zusammenfassung:	Highlights • We studied patients who had HHV-6-reactive OCBs in their CSF. • Most of the patients with HHV-6-reactivity had a demyelinating disease, mostly MS. • Studied patients had significantly more OCBs and were younger than the others.
ISSN:	1386-6532 1873-5967
DOI:	10.1016/j.jcv.2014.07.006