Dexmedetomidine anesthesia enhances spike generation during intra-operative electrocorticography: A promising adjunct for epilepsy surgery

Highlights • Dexmedetomidine infusion provides adequate anesthesia during electrocorticography. • The drug infusion increases spike activity in most of the patients. • The mean spike rates during Dex phase were higher compared to preDEX phase. • Hence, dexmedetomidine is useful during intra-operativ...

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Veröffentlicht in:	Epilepsy research 2015-01, Vol.109, p.65-71
Hauptverfasser:	Chaitanya, G, Arivazhagan, A, Sinha, S, Reddy, K.R. Madhusudan, Thennarasu, K, Bharath, R.D, Rao, M. Bhaskara, Chandramouli, B.A, Satishchandra, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anesthetics Brain - drug effects Brain - physiopathology Brain - surgery Dexmedetomidine Drug-resistant epilepsy Electrocorticography Electroencephalography - methods Epilepsy - physiopathology Epilepsy - surgery Female Humans Intraoperative Neurophysiological Monitoring - methods Male Mesial temporal sclerosis, Anesthesia Neurology Neurosurgical Procedures - methods Prospective Studies
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Zusammenfassung:	Highlights • Dexmedetomidine infusion provides adequate anesthesia during electrocorticography. • The drug infusion increases spike activity in most of the patients. • The mean spike rates during Dex phase were higher compared to preDEX phase. • Hence, dexmedetomidine is useful during intra-operative ECoG in epilepsy surgery.
ISSN:	0920-1211 1872-6844
DOI:	10.1016/j.eplepsyres.2014.10.006