Clinical Care of Two Patients with Ebola Virus Disease in the United States

Treatment of Ebola virus disease is a tremendous challenge for both the patient and the care team. In this report, two patients with EVD were evacuated from Liberia and successfully treated with fluid and electrolyte support and other therapies at Emory University Hospital. The largest outbreak of EVD in history began in December 2013 in Guinea, a country in West Africa. 1 By late March, Liberia had reported seven cases. By the end of May, the epidemic had spread to Sierra Leone. As of November 5, 2014, a total of 13,042 cases of EVD (including 4818 deaths) had been reported in six countries in West Africa (Guinea, Sierra Leone, Liberia, Mali, Nigeria, and Senegal), the United States, and Spain. 2 EVD causes a nonspecific febrile illness associated with myalgia, with progression to gastrointestinal symptoms (abdominal pain, nausea, vomiting, and diarrhea). In the second week of . . .