Cytokeratin 19 expression in primary thoracic tumors and lymph node metastases
Highlights • We performed a large-scale analysis of the CK19 expression in thoracic tumors. • Thoracic tumors except for PCs, CTs, and SCCs were positive for CK19. • We showed the possibility of OSNA method in thoracic tumors. • Inflammatory cells showed weak CK19 staining in primary sites and LNs....
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| Veröffentlicht in: | Lung cancer (Amsterdam, Netherlands) Netherlands), 2014-12, Vol.86 (3), p.318-323 |
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| container_title | Lung cancer (Amsterdam, Netherlands) |
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| creator | Masai, Kyohei Nakagawa, Kazuo Yoshida, Akihiko Sakurai, Hiroyuki Watanabe, Shun-ichi Asamura, Hisao Tsuta, Koji |
| description | Highlights • We performed a large-scale analysis of the CK19 expression in thoracic tumors. • Thoracic tumors except for PCs, CTs, and SCCs were positive for CK19. • We showed the possibility of OSNA method in thoracic tumors. • Inflammatory cells showed weak CK19 staining in primary sites and LNs. |
| doi_str_mv | 10.1016/j.lungcan.2014.09.018 |
| format | Article |
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Malignant lymphomas. Malignant reticulosis. Myelofibrosis ; Lung ; Lymph Nodes - pathology ; Lymph Nodes - surgery ; Lymphatic Metastasis - genetics ; Lymphatic Metastasis - pathology ; Medical sciences ; Nucleic Acid Amplification Techniques ; OSNA ; Pneumology ; Pulmonary/Respiratory ; Thoracic Neoplasms - classification ; Thoracic Neoplasms - genetics ; Thoracic Neoplasms - pathology ; TMA ; Tumors of the respiratory system and mediastinum</subject><ispartof>Lung cancer (Amsterdam, Netherlands), 2014-12, Vol.86 (3), p.318-323</ispartof><rights>Elsevier Ireland Ltd</rights><rights>2014 Elsevier Ireland Ltd</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c586t-51e9d63ee709b304a065e0c22380a7133c98b81d84a215f53efae15209f398c03</citedby><cites>FETCH-LOGICAL-c586t-51e9d63ee709b304a065e0c22380a7133c98b81d84a215f53efae15209f398c03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0169500214004127$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=29034348$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25453845$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Masai, Kyohei</creatorcontrib><creatorcontrib>Nakagawa, Kazuo</creatorcontrib><creatorcontrib>Yoshida, Akihiko</creatorcontrib><creatorcontrib>Sakurai, Hiroyuki</creatorcontrib><creatorcontrib>Watanabe, Shun-ichi</creatorcontrib><creatorcontrib>Asamura, Hisao</creatorcontrib><creatorcontrib>Tsuta, Koji</creatorcontrib><title>Cytokeratin 19 expression in primary thoracic tumors and lymph node metastases</title><title>Lung cancer (Amsterdam, Netherlands)</title><addtitle>Lung Cancer</addtitle><description>Highlights • We performed a large-scale analysis of the CK19 expression in thoracic tumors. • Thoracic tumors except for PCs, CTs, and SCCs were positive for CK19. • We showed the possibility of OSNA method in thoracic tumors. • Inflammatory cells showed weak CK19 staining in primary sites and LNs.</description><subject>Biological and medical sciences</subject><subject>Biomarkers, Tumor - genetics</subject><subject>Breast Neoplasms - genetics</subject><subject>Breast Neoplasms - pathology</subject><subject>CK19</subject><subject>Gene Expression Regulation, Neoplastic</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Hematology, Oncology and Palliative Medicine</subject><subject>Humans</subject><subject>Immunohistochemistry</subject><subject>Intraoperative Period</subject><subject>Keratin-19 - biosynthesis</subject><subject>Keratin-19 - genetics</subject><subject>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</subject><subject>Lung</subject><subject>Lymph Nodes - pathology</subject><subject>Lymph Nodes - surgery</subject><subject>Lymphatic Metastasis - genetics</subject><subject>Lymphatic Metastasis - pathology</subject><subject>Medical sciences</subject><subject>Nucleic Acid Amplification Techniques</subject><subject>OSNA</subject><subject>Pneumology</subject><subject>Pulmonary/Respiratory</subject><subject>Thoracic Neoplasms - classification</subject><subject>Thoracic Neoplasms - genetics</subject><subject>Thoracic Neoplasms - pathology</subject><subject>TMA</subject><subject>Tumors of the respiratory system and mediastinum</subject><issn>0169-5002</issn><issn>1872-8332</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkd-L1DAQx4Mo3t7pn6D0RfCldSY_2uRFORZPhUMf1OeQTade9tp0TVpx_3tbdlXwRQgEwme-M_kMY88QKgSsX-2rfo7fvIsVB5QVmApQP2Ab1A0vtRD8IdssnCkVAL9glznvAbBBMI_ZBVdSCS3Vhn3cHqfxnpKbQizQFPTzkCjnMMZieTikMLh0LKa7MTkffDHNw5hy4WJb9MfhcFfEsaVioMnl5VB-wh51rs_09Hxfsa83b79s35e3n9592F7fll7peioVkmlrQdSA2QmQDmpF4DkXGlyDQnijdxpbLR1H1SlBnSNUHEwnjPYgrtjLU-4hjd9nypMdQvbU9y7SOGeLtTDS1AJXVJ1Qn8acE3X2_CuLYFeVdm_PKu2q0oKxi8ql7vm5xbwbqP1T9dvdArw4Ay5713fJRR_yX86AkEKuQW9OHC1CfgRKNvtA0VMbEvnJtmP47yiv_0nwfYhhaXpPR8r7cU5xsW3RZm7Bfl73vq4dJYBE3ohfF5-oqg</recordid><startdate>20141201</startdate><enddate>20141201</enddate><creator>Masai, Kyohei</creator><creator>Nakagawa, Kazuo</creator><creator>Yoshida, Akihiko</creator><creator>Sakurai, Hiroyuki</creator><creator>Watanabe, Shun-ichi</creator><creator>Asamura, Hisao</creator><creator>Tsuta, Koji</creator><general>Elsevier Ireland Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20141201</creationdate><title>Cytokeratin 19 expression in primary thoracic tumors and lymph node metastases</title><author>Masai, Kyohei ; Nakagawa, Kazuo ; Yoshida, Akihiko ; Sakurai, Hiroyuki ; Watanabe, Shun-ichi ; Asamura, Hisao ; Tsuta, Koji</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c586t-51e9d63ee709b304a065e0c22380a7133c98b81d84a215f53efae15209f398c03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Biological and medical sciences</topic><topic>Biomarkers, Tumor - genetics</topic><topic>Breast Neoplasms - genetics</topic><topic>Breast Neoplasms - pathology</topic><topic>CK19</topic><topic>Gene Expression Regulation, Neoplastic</topic><topic>Hematologic and hematopoietic diseases</topic><topic>Hematology, Oncology and Palliative Medicine</topic><topic>Humans</topic><topic>Immunohistochemistry</topic><topic>Intraoperative Period</topic><topic>Keratin-19 - biosynthesis</topic><topic>Keratin-19 - genetics</topic><topic>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</topic><topic>Lung</topic><topic>Lymph Nodes - pathology</topic><topic>Lymph Nodes - surgery</topic><topic>Lymphatic Metastasis - genetics</topic><topic>Lymphatic Metastasis - pathology</topic><topic>Medical sciences</topic><topic>Nucleic Acid Amplification Techniques</topic><topic>OSNA</topic><topic>Pneumology</topic><topic>Pulmonary/Respiratory</topic><topic>Thoracic Neoplasms - classification</topic><topic>Thoracic Neoplasms - genetics</topic><topic>Thoracic Neoplasms - pathology</topic><topic>TMA</topic><topic>Tumors of the respiratory system and mediastinum</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Masai, Kyohei</creatorcontrib><creatorcontrib>Nakagawa, Kazuo</creatorcontrib><creatorcontrib>Yoshida, Akihiko</creatorcontrib><creatorcontrib>Sakurai, Hiroyuki</creatorcontrib><creatorcontrib>Watanabe, Shun-ichi</creatorcontrib><creatorcontrib>Asamura, Hisao</creatorcontrib><creatorcontrib>Tsuta, Koji</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Lung cancer (Amsterdam, Netherlands)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Masai, Kyohei</au><au>Nakagawa, Kazuo</au><au>Yoshida, Akihiko</au><au>Sakurai, Hiroyuki</au><au>Watanabe, Shun-ichi</au><au>Asamura, Hisao</au><au>Tsuta, Koji</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cytokeratin 19 expression in primary thoracic tumors and lymph node metastases</atitle><jtitle>Lung cancer (Amsterdam, Netherlands)</jtitle><addtitle>Lung Cancer</addtitle><date>2014-12-01</date><risdate>2014</risdate><volume>86</volume><issue>3</issue><spage>318</spage><epage>323</epage><pages>318-323</pages><issn>0169-5002</issn><eissn>1872-8332</eissn><coden>LUCAE5</coden><abstract>Highlights • We performed a large-scale analysis of the CK19 expression in thoracic tumors. • Thoracic tumors except for PCs, CTs, and SCCs were positive for CK19. • We showed the possibility of OSNA method in thoracic tumors. • Inflammatory cells showed weak CK19 staining in primary sites and LNs.</abstract><cop>Oxford</cop><pub>Elsevier Ireland Ltd</pub><pmid>25453845</pmid><doi>10.1016/j.lungcan.2014.09.018</doi><tpages>6</tpages></addata></record> |
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| subjects | Biological and medical sciences Biomarkers, Tumor - genetics Breast Neoplasms - genetics Breast Neoplasms - pathology CK19 Gene Expression Regulation, Neoplastic Hematologic and hematopoietic diseases Hematology, Oncology and Palliative Medicine Humans Immunohistochemistry Intraoperative Period Keratin-19 - biosynthesis Keratin-19 - genetics Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lung Lymph Nodes - pathology Lymph Nodes - surgery Lymphatic Metastasis - genetics Lymphatic Metastasis - pathology Medical sciences Nucleic Acid Amplification Techniques OSNA Pneumology Pulmonary/Respiratory Thoracic Neoplasms - classification Thoracic Neoplasms - genetics Thoracic Neoplasms - pathology TMA Tumors of the respiratory system and mediastinum |
| title | Cytokeratin 19 expression in primary thoracic tumors and lymph node metastases |
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