Distribution of orexin-1 receptor-green fluorescent protein- (OX1 -GFP) expressing neurons in the mouse brain stem and pons: Co-localization with tyrosine hydroxylase and neuronal nitric oxide synthase

Highlights • OX1 receptors are expressed in the mouse medulla and pons. • OX1 receptor expression greatest in the locus coeruleus and dorsal raphe nucleus. • Extensive co-expression of OX1 receptors and tyrosine hydroxylase was observed. • OX1 and NOS1 co-localization most prominent in the pedunculo...

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Veröffentlicht in:	Neuroscience 2014-10, Vol.278, p.253-264
Hauptverfasser:	Darwinkel, A, Stanić, D, Booth, L.C, May, C.N, Lawrence, A.J, Yao, S.T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain Stem - metabolism green fluorescent protein Green Fluorescent Proteins - analysis immunohistochemistry Male medulla oblongata Mice Mice, Transgenic Neurology Neurons - metabolism Nitric Oxide Synthase Type I - analysis orexin Orexin Receptors - analysis Pons - metabolism receptor Tyrosine 3-Monooxygenase - analysis
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Beschreibung
Zusammenfassung:	Highlights • OX1 receptors are expressed in the mouse medulla and pons. • OX1 receptor expression greatest in the locus coeruleus and dorsal raphe nucleus. • Extensive co-expression of OX1 receptors and tyrosine hydroxylase was observed. • OX1 and NOS1 co-localization most prominent in the pedunculopontine tegmental area.
ISSN:	0306-4522 1873-7544
DOI:	10.1016/j.neuroscience.2014.08.027