Evaluation of bacterial growth inhibition by mercaptopropionic acid in metallo- beta -lactamase detection on multidrug-resistant Acinetobacter baumannii

Evaluation of bacterial growth inhibition by mercaptopropionic acid in metallo- beta -lactamase detection on multidrug-resistant Acinetobacter baumannii

INTRODUCTION: Metallo- beta -lactamase (MBL) has been reported all over the world. METHODS: The inhibitory effect of mercaptopropionic acid (MPA) on bacterial growth was evaluated by comparison between disk diffusion and broth dilution methodology with determination of the minimum inhibitory concent...

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Veröffentlicht in:Revista da Sociedade Brasileira de Medicina Tropical 2012-03, Vol.45 (2), p.253-254
Hauptverfasser: Mayer, Leticia Eichstaedt, Horner, Rosmari, Tizotti, Maisa Kraulich, Martini, Rosieli, Souza Marques Roehrs, Magda Cristina, Barbisan Kempfer, Claudia
Format: Artikel
Sprache:eng
Schlagworte:
Acinetobacter
Acinetobacter baumannii
Bacteria
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Zusammenfassung:INTRODUCTION: Metallo- beta -lactamase (MBL) has been reported all over the world. METHODS: The inhibitory effect of mercaptopropionic acid (MPA) on bacterial growth was evaluated by comparison between disk diffusion and broth dilution methodology with determination of the minimum inhibitory concentration (MIC) for multidrug-resistant Acinetobacter baumanni strains. RESULTS: MPA significantly inhibited growth of the strains. CONCLUSIONS: The use of MPA can affect the results in phenotypic methods of MBL detection.
ISSN:0037-8682
1678-9849
DOI:10.1590/S0037-8682201200020002